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The role of the poor metabolizer genotype CYP2D6 and CYP1A2 phenotype in the pharmacokinetics of duloxetine and venlafaxine-A case report.
Kuzin, Maxim; Scharrer, Isabel; Nolan, Daniele; Baumgartner, Markus; Paulzen, Michael; Schoretsanitis, Georgios; Xepapadakos, Franziskos.
Affiliation
  • Kuzin M; Clienia Schloessli, Private Psychiatric Hospital and Academic Teaching Hospital of the University of Zurich, Oetwil am See, Zurich, Switzerland.
  • Scharrer I; Clienia Schloessli, Private Psychiatric Hospital and Academic Teaching Hospital of the University of Zurich, Oetwil am See, Zurich, Switzerland.
  • Nolan D; Clienia Schloessli, Private Psychiatric Hospital and Academic Teaching Hospital of the University of Zurich, Oetwil am See, Zurich, Switzerland.
  • Baumgartner M; Clienia Schloessli, Private Psychiatric Hospital and Academic Teaching Hospital of the University of Zurich, Oetwil am See, Zurich, Switzerland.
  • Paulzen M; Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen University, Aachen, Germany.
  • Schoretsanitis G; JARA - Translational Brain Medicine, Jülich, Germany.
  • Xepapadakos F; Alexianer Hospital Aachen, Aachen, Germany.
Basic Clin Pharmacol Toxicol ; 127(4): 354-357, 2020 10.
Article in En | MEDLINE | ID: mdl-32365274
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 CYP1A2 / Cytochrome P-450 CYP2D6 / Depression / Venlafaxine Hydrochloride / Duloxetine Hydrochloride / Serotonin and Noradrenaline Reuptake Inhibitors / Pharmacogenomic Variants Type of study: Diagnostic_studies Limits: Adult / Female / Humans Language: En Journal: Basic Clin Pharmacol Toxicol Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2020 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 CYP1A2 / Cytochrome P-450 CYP2D6 / Depression / Venlafaxine Hydrochloride / Duloxetine Hydrochloride / Serotonin and Noradrenaline Reuptake Inhibitors / Pharmacogenomic Variants Type of study: Diagnostic_studies Limits: Adult / Female / Humans Language: En Journal: Basic Clin Pharmacol Toxicol Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2020 Document type: Article Affiliation country: Switzerland Country of publication: United kingdom