German population data for 18 X-STRs: a hexaplex PCR adding two clusters of X-STRs to the Argus X-12 set and expanding the German haplotype databases.
Int J Legal Med
; 134(6): 2061-2062, 2020 Nov.
Article
in En
| MEDLINE
| ID: mdl-32367330
ABSTRACT
In kinship analysis, large data sets with estimated haplotype frequencies for marker clusters are very important for the likelihood calculation. Practical use of the X-STRs demonstrated that in some complex kinship cases, the marker set of the Investigator Argus X-12 kit can be insufficient. This study aimed to extend the German data base of the Argus X-12 kit (1037 haplotypes) and for a cluster in Xq21 (806 haplotypes) with additional 700 male haplotypes and to include a further cluster in Xp22.3 to complete the X-STR marker set for complex kinship cases.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Haplotypes
/
Linkage Disequilibrium
/
Polymerase Chain Reaction
/
Microsatellite Repeats
/
Chromosomes, Human, X
/
Genetic Linkage
Limits:
Humans
/
Male
Country/Region as subject:
Europa
Language:
En
Journal:
Int J Legal Med
Journal subject:
JURISPRUDENCIA
Year:
2020
Document type:
Article
Affiliation country:
Germany