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The Society for Immunotherapy of Cancer perspective on regulation of interleukin-6 signaling in COVID-19-related systemic inflammatory response.
Arnaldez, Fernanda I; O'Day, Steven J; Drake, Charles G; Fox, Bernard A; Fu, Bingqing; Urba, Walter J; Montesarchio, Vincenzo; Weber, Jeffrey S; Wei, Haiming; Wigginton, Jon M; Ascierto, Paolo Antonio.
Affiliation
  • Arnaldez FI; MacroGenics Inc, Rockville, Maryland, USA.
  • O'Day SJ; John Wayne Cancer Institute and Cancer Clinic, Providence Saint John's Health Center, Santa Monica, California, United States.
  • Drake CG; Providence Los Angeles Metro Hospitals, Santa Monica, California, United States.
  • Fox BA; Herbert Irving Cancer Center, Columbia University Medical Center, New York, New York, USA.
  • Fu B; Earle A Chiles Research Institute, Portland, Oregon, USA.
  • Urba WJ; University of Science and Technology of China, Hefei, Anhui, China.
  • Montesarchio V; Earle A Chiles Research Institute, Portland, Oregon, USA.
  • Weber JS; A.O.R.N. dei Colli Monaldi-Cotugno-CTO Hospitals, Naples, Italy.
  • Wei H; Perlmutter Cancer Center, NYU Langone Health, New York, New York, USA.
  • Wigginton JM; University of Science and Technology of China, Hefei, Anhui, China.
  • Ascierto PA; Frederick, Maryland, USA.
J Immunother Cancer ; 8(1)2020 05.
Article in En | MEDLINE | ID: mdl-32385146
Subject(s)
Coronavirus Infections/complications; Coronavirus Infections/drug therapy; Immunotherapy; Interleukin-6/antagonists & inhibitors; Interleukin-6/immunology; Pneumonia, Viral/complications; Pneumonia, Viral/drug therapy; Respiratory Distress Syndrome/complications; Respiratory Distress Syndrome/drug therapy; Societies, Medical; Adoptive Transfer; Antibodies, Monoclonal/pharmacology; Antibodies, Monoclonal/therapeutic use; Antibodies, Monoclonal, Humanized/pharmacology; Antibodies, Monoclonal, Humanized/therapeutic use; COVID-19; Coronavirus Infections/immunology; Coronavirus Infections/pathology; Cytokine Release Syndrome/complications; Cytokine Release Syndrome/drug therapy; Cytokine Release Syndrome/immunology; Cytokine Release Syndrome/pathology; Granulocyte-Macrophage Colony-Stimulating Factor/antagonists & inhibitors; Humans; Inflammation/complications; Inflammation/drug therapy; Inflammation/immunology; Inflammation/pathology; Interferon-gamma/antagonists & inhibitors; Interleukin-1/antagonists & inhibitors; Interleukin-17/antagonists & inhibitors; Interleukin-23/antagonists & inhibitors; Interleukin-6/genetics; Interleukin-6/metabolism; Janus Kinases/antagonists & inhibitors; Neoplasms/immunology; Neoplasms/therapy; Pandemics; Pneumonia, Viral/immunology; Pneumonia, Viral/pathology; Respiratory Distress Syndrome/immunology; Respiratory Distress Syndrome/pathology; STAT Transcription Factors/antagonists & inhibitors; Severe Acute Respiratory Syndrome/pathology; Signal Transduction/drug effects; Tumor Necrosis Factor-alpha/antagonists & inhibitors
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Distress Syndrome / Societies, Medical / Interleukin-6 / Coronavirus Infections / Immunotherapy Type of study: Prognostic_studies Language: En Journal: J Immunother Cancer Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Distress Syndrome / Societies, Medical / Interleukin-6 / Coronavirus Infections / Immunotherapy Type of study: Prognostic_studies Language: En Journal: J Immunother Cancer Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom