PPAR&#945; plays an important role in the migration activity, and the expression of CYP2S1 and CYP1B1 in chrysin-treated HCT116 cells.

Khor, Chin Yin; Khoo, Boon Yin

PPARα plays an important role in the migration activity, and the expression of CYP2S1 and CYP1B1 in chrysin-treated HCT116 cells.

Khor, Chin Yin; Khoo, Boon Yin.

Affiliation

Khor CY; Institute for Research in Molecular Medicine (INFORMM), Universitit Sains Malaysia, 11800, Penang, Malaysia.
Khoo BY; Institute for Research in Molecular Medicine (INFORMM), Universitit Sains Malaysia, 11800, Penang, Malaysia. boonyin@usm.my.

Biotechnol Lett ; 42(8): 1581-1595, 2020 Aug.

Article in En | MEDLINE | ID: mdl-32385743

Subject(s)

Cell Movement; Cytochrome P-450 CYP1B1/metabolism; Cytochrome P-450 Enzyme System/metabolism; Flavonoids/pharmacology; PPAR alpha/metabolism; Cell Cycle/drug effects; Cell Cycle/physiology; Cell Movement/drug effects; Cell Movement/physiology; Cytochrome P-450 CYP1B1/analysis; Cytochrome P-450 CYP1B1/genetics; Cytochrome P-450 Enzyme System/analysis; Cytochrome P-450 Enzyme System/genetics; Flavonoids/pharmacokinetics; HCT116 Cells; Humans; PPAR alpha/analysis; PPAR alpha/genetics

Key words

Anticancer agent; Camptothecin; Chrysin; Drug metabolism; HCT116 cells; PPARα

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Flavonoids / Cell Movement / Cytochrome P-450 Enzyme System / PPAR alpha / Cytochrome P-450 CYP1B1 Limits: Humans Language: En Journal: Biotechnol Lett Year: 2020 Document type: Article Affiliation country: Malaysia Country of publication: Netherlands

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