A Novel Scaffold-Based Hybrid Multicellular Model for Pancreatic Ductal Adenocarcinoma-Toward a Better Mimicry of the <i>in vivo</i> Tumor Microenvironment.

Gupta, Priyanka; Pérez-Mancera, Pedro A; Kocher, Hemant; Nisbet, Andrew; Schettino, Giuseppe; Velliou, Eirini G

A Novel Scaffold-Based Hybrid Multicellular Model for Pancreatic Ductal Adenocarcinoma-Toward a Better Mimicry of the in vivo Tumor Microenvironment.

Gupta, Priyanka; Pérez-Mancera, Pedro A; Kocher, Hemant; Nisbet, Andrew; Schettino, Giuseppe; Velliou, Eirini G.

Affiliation

Gupta P; Bioprocess and Biochemical Engineering Group (BioProChem), Department of Chemical and Process Engineering, University of Surrey, Guildford, United Kingdom.
Pérez-Mancera PA; Department of Molecular and Clinical Cancer Medicine, University of Liverpool, Liverpool, United Kingdom.
Kocher H; Centre for Tumour Biology and Experimental Cancer Medicine, Barts Cancer Institute, Queen Mary University of London, London, United Kingdom.
Nisbet A; Department of Medical Physics and Biomedical Engineering, University College London, London, United Kingdom.
Schettino G; Department of Physics, University of Surrey, Guildford, United Kingdom.
Velliou EG; Medical Radiation Science Group, The National Physical Laboratory, Teddington, United Kingdom.

Front Bioeng Biotechnol ; 8: 290, 2020.

Article in En | MEDLINE | ID: mdl-32391339

Key words

3D model; endothelial cells; multicellular tumor model; pancreatic cancer; pancreatic stellate cells; polyurethane scaffold; scaffold-assisted tumor model

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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: Front Bioeng Biotechnol Year: 2020 Document type: Article Affiliation country: United kingdom Country of publication: Switzerland

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