Fabrication of abamectin-loaded mesoporous silica nanoparticles by emulsion-solvent evaporation to improve photolysis stability and extend insecticidal activity.
Nanotechnology
; 31(34): 345705, 2020 Aug 21.
Article
in En
| MEDLINE
| ID: mdl-32392541
ABSTRACT
Mesoporous silica nanoparticles (MSNs) can be designed to effectively load, protect, and control the release of pesticides. In this study, emulsion-solvent evaporation was used to fabricate abamectin-loaded MSNs. Our method could deliver abamectin in the process of MSN self-assembly, resulting in simple operation, short preparation period, and outstanding drug carrying capacity. The characteristics of abamectin-loaded MSNs, including morphology, loading content, stability against photolysis, controlled release behavior, and toxicological effect, were systematically investigated. Abamectin-loaded MSNs were successfully produced, having spherical shape, rough surface, uniform particle sizes, typically hollow structure, high loading efficiency (44.8%), excellent photodegradation-reducing ability, and controlled-release properties. The biological activity survey for abamectin-loaded MSNs showed excellent toxicological properties against Plutella xylostella larvae, and maintained biological activity until the 15th day, with 70% mortality of the target insect. The results of this study are beneficial for the development of a delivery system for the rational and effective usage of pesticides.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Ivermectin
/
Silicon Dioxide
/
Insecticides
/
Moths
Limits:
Animals
Language:
En
Journal:
Nanotechnology
Year:
2020
Document type:
Article
Publication country:
ENGLAND
/
ESCOCIA
/
GB
/
GREAT BRITAIN
/
INGLATERRA
/
REINO UNIDO
/
SCOTLAND
/
UK
/
UNITED KINGDOM