Role of Extrinsic Apoptotic Signaling Pathway during Definitive Erythropoiesis in Normal Patients and in Patients with ß-Thalassemia.

Raducka-Jaszul, Olga; Boguslawska, Dzamila M; Jedruchniewicz, Natalia; Sikorski, Aleksander F

Raducka-Jaszul, Olga; Boguslawska, Dzamila M; Jedruchniewicz, Natalia; Sikorski, Aleksander F.

Affiliation

Raducka-Jaszul O; Department of Cytobiochemistry, Biotechnology Faculty, University of Wroclaw, Joliot-Curie 14a, 50-383 Wroclaw, Poland.
Boguslawska DM; Department of Biotechnology, Faculty of Biological Sciences, University of Zielona Góra, Szafrana 1, 65-516 Zielona Góra, Poland.
Jedruchniewicz N; Research and Development Center, Regional Specialist Hospital, Kamienskiego 73a, 51-154 Wroclaw, Poland.
Sikorski AF; Research and Development Center, Regional Specialist Hospital, Kamienskiego 73a, 51-154 Wroclaw, Poland.

Int J Mol Sci ; 21(9)2020 May 08.

Article in En | MEDLINE | ID: mdl-32397135

Subject(s)

Apoptosis/drug effects; Apoptosis/genetics; Erythropoiesis/genetics; Signal Transduction/genetics; beta-Thalassemia/blood; Caspases/metabolism; Death Effector Domain/genetics; Erythrocytes/drug effects; Erythrocytes/metabolism; Erythropoiesis/drug effects; Fas Ligand Protein/metabolism; Humans; Signal Transduction/drug effects; TNF-Related Apoptosis-Inducing Ligand/metabolism; Tumor Necrosis Factor-alpha/metabolism; Tumor Necrosis Factor-alpha/pharmacology; beta-Thalassemia/genetics

Key words

Fas/FasL; TRAIL/TRAILR; apoptosis: apoptotic extrinsic pathway; death domains; erythropoiesis; ß-thalassemia

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Beta-Thalassemia / Apoptosis / Erythropoiesis Limits: Humans Language: En Journal: Int J Mol Sci Year: 2020 Document type: Article Affiliation country: Poland

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