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Maydisone, a novel oxime polyketide from the cultures of Bipolaris maydis.
Tran, Thi-Minh-Dinh; Nguyen, Van-Kieu; Duong, Thuc-Huy; Tran, Thanh-Nha; Nguyen, Ngoc-Hong; Devi, Asshaima Paramita; Chavasiri, Warinthorn; Dinh, Minh-Hiep; Tran, Nguyen-Minh-An; Sichaem, Jirapast.
Affiliation
  • Tran TM; Department of Biology, University of Education, Ho Chi Minh City, Vietnam.
  • Nguyen VK; Institute of Fundamental and Applied Sciences, Duy Tan University, Ho Chi Minh City, Vietnam.
  • Duong TH; Faculty of Natural Sciences, Duy Tan University, Da Nang, Vietnam.
  • Tran TN; Department of Chemistry, University of Education, Ho Chi Minh City, Vietnam.
  • Nguyen NH; Department of Chemistry, University of Education, Ho Chi Minh City, Vietnam.
  • Devi AP; CirTech Institute, Ho Chi Minh City University of Technology (HUTECH), Ho Chi Minh City, Vietnam.
  • Chavasiri W; Faculty of Science, Department of Chemistry, Center of Excellence in Natural Products Chemistry, Chulalongkorn University, Bangkok, Thailand.
  • Dinh MH; Faculty of Science, Department of Chemistry, Center of Excellence in Natural Products Chemistry, Chulalongkorn University, Bangkok, Thailand.
  • Tran NM; Management Board, Agricultural Hi-Tech Park, Ho Chi Minh City, Vietnam.
  • Sichaem J; Faculty of Chemical Engineering, Industrial University of Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Nat Prod Res ; 36(1): 102-107, 2022 Jan.
Article in En | MEDLINE | ID: mdl-32400180
ABSTRACT
A novel oxime polyketide, maydisone (1), along with two known compounds, 7-hydroxy-2,5-dimethylchromone (2) and 2,5-dimethylbenzoic acid (3) were isolated from the cultures of Bipolaris maydis. Their structures were identified by the application of NMR and MS data analyses and comparison with previous reports. Compound 1 showed the most powerful inhibition of α-glucosidase, with an IC50 value of 68.30 ± 0.83 µM.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyketides Language: En Journal: Nat Prod Res Year: 2022 Document type: Article Affiliation country: Vietnam
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyketides Language: En Journal: Nat Prod Res Year: 2022 Document type: Article Affiliation country: Vietnam