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Glucose Response by Stem Cell-Derived ß Cells In Vitro Is Inhibited by a Bottleneck in Glycolysis.
Davis, Jeffrey C; Alves, Tiago C; Helman, Aharon; Chen, Jonathan C; Kenty, Jennifer H; Cardone, Rebecca L; Liu, David R; Kibbey, Richard G; Melton, Douglas A.
Affiliation
  • Davis JC; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA.
  • Alves TC; Department of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA; Institute for Clinical Chemistry and Laboratory Medicine, Technische Universität Dresden, Dresden, Germany.
  • Helman A; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA.
  • Chen JC; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA.
  • Kenty JH; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA.
  • Cardone RL; Department of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA.
  • Liu DR; Merkin Institute of Transformative Technologies in Healthcare, Broad Institute of Harvard and MIT, Cambridge, MA, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA.
  • Kibbey RG; Department of Internal Medicine (Endocrinology), Yale University, New Haven, CT, USA; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT, USA.
  • Melton DA; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA; Howard Hughes Medical Institute, Chevy Chase, MD, USA. Electronic address: dmelton@harvard.edu.
Cell Rep ; 31(6): 107623, 2020 05 12.
Article in En | MEDLINE | ID: mdl-32402282
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / B-Lymphocytes / Glucose / Glycolysis Limits: Animals / Humans Language: En Journal: Cell Rep Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Stem Cells / B-Lymphocytes / Glucose / Glycolysis Limits: Animals / Humans Language: En Journal: Cell Rep Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States