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Chronic polypharmacy impairs explorative behavior and reduces synaptic functions in young adult mice.
Eroli, Francesca; Johnell, Kristina; Latorre Leal, María; Adamo, Chiara; Hilmer, Sarah; Wastesson, Jonas W; Cedazo-Minguez, Angel; Maioli, Silvia.
Affiliation
  • Eroli F; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Solna, Sweden.
  • Johnell K; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Latorre Leal M; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Solna, Sweden.
  • Adamo C; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Solna, Sweden.
  • Hilmer S; Kolling Institute, Royal North Shore Hosptial and University of Sydney, Clinical Pharmacology and Aged Care, Sidney, Australia.
  • Wastesson JW; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
  • Cedazo-Minguez A; Aging Research Center, Karolinska Institutet and Stockholm University, Stockholm, Sweden.
  • Maioli S; Karolinska Institutet, Department of Neurobiology, Care Sciences and Society, Center for Alzheimer Research, Division of Neurogeriatrics, Solna, Sweden.
Aging (Albany NY) ; 12(11): 10147-10161, 2020 05 22.
Article in En | MEDLINE | ID: mdl-32445552
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Polypharmacy / Exploratory Behavior / Memory Disorders Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Animals / Humans / Male Language: En Journal: Aging (Albany NY) Journal subject: GERIATRIA Year: 2020 Document type: Article Affiliation country: Sweden Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Polypharmacy / Exploratory Behavior / Memory Disorders Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Animals / Humans / Male Language: En Journal: Aging (Albany NY) Journal subject: GERIATRIA Year: 2020 Document type: Article Affiliation country: Sweden Country of publication: United States