Fluorogenic iminosydnones: bioorthogonal tools for double turn-on click-and-release reactions.
Chem Commun (Camb)
; 56(52): 7183-7186, 2020 Jul 04.
Article
in En
| MEDLINE
| ID: mdl-32463407
ABSTRACT
In this article, we report the synthesis and use of iminosydnone-based profluorophores as bioorthogonal cleavable linkers for imaging applications. These linkers react with cycloalkynes via subsequent [3+2] cycloaddition and retro Diels-Alder reactions, allowing simultaneous release of two dyes in biological media.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Sydnones
/
Fluorescent Dyes
Limits:
Animals
Language:
En
Journal:
Chem Commun (Camb)
Journal subject:
QUIMICA
Year:
2020
Document type:
Article
Affiliation country:
France