ß<sup>2</sup>-<i>Homo</i>-Amino Acid Scan of µ-Selective Opioid Tetrapeptide TAPP.

Tymecka, Dagmara; Lipinski, Piotr F J; Kosson, Piotr; Misicka, Aleksandra

ß²-Homo-Amino Acid Scan of µ-Selective Opioid Tetrapeptide TAPP.

Tymecka, Dagmara; Lipinski, Piotr F J; Kosson, Piotr; Misicka, Aleksandra.

Affiliation

Tymecka D; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.
Lipinski PFJ; Department of Neuropeptides, Mossakowski Medical Research Centre Polish Academy of Sciences, Pawinskiego 5, 02-106 Warsaw, Poland.
Kosson P; Toxicology Research Laboratory, Mossakowski Medical Research Centre Polish Academy of Sciences, Pawinskiego 5, 02-106 Warsaw, Poland.
Misicka A; Faculty of Chemistry, University of Warsaw, Pasteura 1, 02-093 Warsaw, Poland.

Molecules ; 25(10)2020 May 25.

Article in En | MEDLINE | ID: mdl-32466333

Subject(s)

Amino Acids/chemistry; Aspartic Acid/chemistry; Oligopeptides/chemistry; Receptors, Opioid, delta/chemistry; Receptors, Opioid, mu/chemistry; Amino Acids/metabolism; Animals; Aspartic Acid/metabolism; Binding Sites; Humans; Ligands; Molecular Docking Simulation; Oligopeptides/blood; Protein Binding; Protein Conformation, alpha-Helical; Protein Conformation, beta-Strand; Protein Interaction Domains and Motifs; Protein Stability; Receptors, Opioid, delta/metabolism; Receptors, Opioid, mu/metabolism; Stereoisomerism

Key words

TAPP; opioid peptides; racemic synthesis of ß2-amino acids; µ-opioid receptor; ß2-Homo-amino acids; ß2-amino acids

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oligopeptides / Aspartic Acid / Receptors, Opioid, delta / Receptors, Opioid, mu / Amino Acids Limits: Animals / Humans Language: En Journal: Molecules Journal subject: BIOLOGIA Year: 2020 Document type: Article Affiliation country: Poland

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