Flame Figures in Linear Immunoglobulin A Bullous Dermatosis Secondary to Parvovirus B19 Infection.
Am J Dermatopathol
; 43(1): 60-62, 2021 Jan 01.
Article
in En
| MEDLINE
| ID: mdl-32472771
ABSTRACT
ABSTRACT Flame figures represent a characteristic but nondiagnostic histological finding in eosinophilic dermatoses. Some bullous autoimmune diseases with a predominant eosinophilic infiltrate, such as bullous pemphigoid, pemphigoid gestationis, and pemphigus vegetans, may show them. However, it is rare to find them in predominant neutrophilic bullous dermatoses such as linear immunoglobulin A. We present a 60-year-old man with a history of chronic urticaria, which presented a bullous disease after an acute parvovirus B19 infection. The histological findings showed an exceptional linear immunoglobulin A bullous dermatosis with an eosinophilic infiltrate in the dermis forming "flame figures." The clinical and histopathological findings for this entity may be identical to those of other dermatoses. For this reason, combining these findings with direct immunofluorescence analysis is essential for correct diagnosis of this bullous disease.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Skin
/
Parvovirus B19, Human
/
Erythema Infectiosum
/
Eosinophils
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Linear IgA Bullous Dermatosis
Type of study:
Diagnostic_studies
Limits:
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Am J Dermatopathol
Year:
2021
Document type:
Article