Oncological results of salvage treatment in patients with hypopharyngeal carcinoma. / Resultados oncológicos del tratamiento de rescate en pacientes con carcinomas de hipofaringe.
Acta Otorrinolaringol Esp (Engl Ed)
; 72(2): 85-91, 2021.
Article
in En, Es
| MEDLINE
| ID: mdl-32473712
ABSTRACT
INTRODUCTION AND OBJECTIVE:
The aim of this study is to analyse the variables related to the feasibility of salvage surgery with radical intention in patients with a local recurrence of hypopharyngeal carcinoma, and to evaluate the oncological performance of this type of surgery.METHODS:
Retrospective study of 96 patients with hypopharyngeal carcinoma with local tumour recurrenceRESULT:
Only 27 patients (28.1%) were considered for surgical salvage treatment. The variables related to feasibility of salvage surgery were non-surgical initial treatment of the tumour and a disease-free interval greater than 6 months. All 69 patients non-candidates for salvage surgery died as a result of tumour progression in a period of less than 2.5 years. The 5-year disease-specific survival rate for the patients treated with salvage surgery was 39.5%. The only variable significantly related to disease-specific survival was the status of the resection margins. Patients with extensive tumour recurrence (rT3-T4) or with simultaneous nodal involvement had a lower survival rate, but the differences did not reach statistical significance.CONCLUSION:
Only 28% of the patients with hypopharyngeal carcinoma with local recurrence of the tumour were eligible for salvage surgery with radical intention. The patients treated with salvage surgery had a 5 -year disease-specific survival of 39.5%.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Type of study:
Observational_studies
Language:
En
/
Es
Journal:
Acta Otorrinolaringol Esp (Engl Ed)
Year:
2021
Document type:
Article