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Genotype-Guided Dosing of Warfarin in Chinese Adults: A Multicenter Randomized Clinical Trial.
Guo, Chengxian; Kuang, Yun; Zhou, Honghao; Yuan, Hong; Pei, Qi; Li, Jingle; Jiang, Weihong; Ng, Chee M; Chen, Xiaoping; Huo, Yong; Cui, Yimin; Wang, Xiaobin; Yu, Jingjing; Sun, Xue; Yu, Wanying; Chen, Peng; Miao, Da; Liu, Wenyu; Yu, Zaixin; Ouyang, Zewei; Shi, Xiangjiang; Lv, Chunmei; Peng, Zijing; Xiong, Guozuo; Zeng, Gaofeng; Zeng, Jianping; Dai, Haiying; Peng, Jianqiang; Zhang, Yuming; Xu, Fanghua; Wu, Jie; Chen, Xiaoliang; Gong, Hao; Yang, Zhiyuan; Wu, Xianming; Fang, Qiulian; Yang, Liu; Li, Haigang; Tan, Hongyi; Huang, Zhijun; Tang, Xiaohong; Yang, Qiong; Tu, Shan; Wang, Xiaoyan; Xiang, Yuxia; Huang, Jie; Wang, Xiaomin; Cai, Jingjing; Jiang, Shanjie; Huang, Lu.
Affiliation
  • Guo C; Center of Clinical Pharmacology, the Third Xiangya Hospital (C.G., Y.K., H.Y., J.Y., X. Sun, W.Y., P.C., D.M., W.L., H.T., Z.H., Y.X., J.H., Xiaomin Wang, L.G., C.Z., G.Y.), Central South University, Changsha, China.
  • Kuang Y; Department of Pharmacy (C.G., Q.P., L.H., Jinfu Peng, G.Y.), Central South University, Changsha, China.
  • Zhou H; Research Center of Drug Clinical Evaluation (C.G., Y.K., G.Y.), Central South University, Changsha, China.
  • Yuan H; Center of Clinical Pharmacology, the Third Xiangya Hospital (C.G., Y.K., H.Y., J.Y., X. Sun, W.Y., P.C., D.M., W.L., H.T., Z.H., Y.X., J.H., Xiaomin Wang, L.G., C.Z., G.Y.), Central South University, Changsha, China.
  • Pei Q; Research Center of Drug Clinical Evaluation (C.G., Y.K., G.Y.), Central South University, Changsha, China.
  • Li J; Department of Clinical Pharmacology, Xiangya Hospital (H.Z., Xiaoping Chen), Central South University, Changsha, China.
  • Jiang W; Center of Clinical Pharmacology, the Third Xiangya Hospital (C.G., Y.K., H.Y., J.Y., X. Sun, W.Y., P.C., D.M., W.L., H.T., Z.H., Y.X., J.H., Xiaomin Wang, L.G., C.Z., G.Y.), Central South University, Changsha, China.
  • Ng CM; Department of Pharmacy (C.G., Q.P., L.H., Jinfu Peng, G.Y.), Central South University, Changsha, China.
  • Chen X; Department of Cardiology, The Third Xiangya Hospital (J.L., W.J., X.T., Q.Y., S.T., Xiaoyan Wang, J.C., S.J.), Central South University, Changsha, China.
  • Huo Y; Department of Cardiology, The Third Xiangya Hospital (J.L., W.J., X.T., Q.Y., S.T., Xiaoyan Wang, J.C., S.J.), Central South University, Changsha, China.
  • Cui Y; College of Pharmacy, University of Kentucky, Lexington (C.M.N.).
  • Wang X; Department of Clinical Pharmacology, Xiangya Hospital (H.Z., Xiaoping Chen), Central South University, Changsha, China.
  • Yu J; Institute of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics (Xiaoping Chen).
  • Sun X; Department of Cardiology (Y.H.), Peking University Health Science Center, Beijing, China.
  • Yu W; Department of Pharmacy, Peking University First Hospital (Y.C.), Peking University Health Science Center, Beijing, China.
  • Chen P; Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmaceutical Sciences (Y.C.), Peking University Health Science Center, Beijing, China.
  • Miao D; Department of Population, Family and Reproductive Health, Center on the Early Life Origins of Disease, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD (Xiaobin Wang).
  • Liu W; Division of General Pediatrics and Adolescent Medicine, Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD (Xiaobin Wang).
  • Yu Z; Center of Clinical Pharmacology, the Third Xiangya Hospital (C.G., Y.K., H.Y., J.Y., X. Sun, W.Y., P.C., D.M., W.L., H.T., Z.H., Y.X., J.H., Xiaomin Wang, L.G., C.Z., G.Y.), Central South University, Changsha, China.
  • Ouyang Z; Center of Clinical Pharmacology, the Third Xiangya Hospital (C.G., Y.K., H.Y., J.Y., X. Sun, W.Y., P.C., D.M., W.L., H.T., Z.H., Y.X., J.H., Xiaomin Wang, L.G., C.Z., G.Y.), Central South University, Changsha, China.
  • Shi X; Center of Clinical Pharmacology, the Third Xiangya Hospital (C.G., Y.K., H.Y., J.Y., X. Sun, W.Y., P.C., D.M., W.L., H.T., Z.H., Y.X., J.H., Xiaomin Wang, L.G., C.Z., G.Y.), Central South University, Changsha, China.
  • Lv C; Center of Clinical Pharmacology, the Third Xiangya Hospital (C.G., Y.K., H.Y., J.Y., X. Sun, W.Y., P.C., D.M., W.L., H.T., Z.H., Y.X., J.H., Xiaomin Wang, L.G., C.Z., G.Y.), Central South University, Changsha, China.
  • Peng Z; Center of Clinical Pharmacology, the Third Xiangya Hospital (C.G., Y.K., H.Y., J.Y., X. Sun, W.Y., P.C., D.M., W.L., H.T., Z.H., Y.X., J.H., Xiaomin Wang, L.G., C.Z., G.Y.), Central South University, Changsha, China.
  • Xiong G; Center of Clinical Pharmacology, the Third Xiangya Hospital (C.G., Y.K., H.Y., J.Y., X. Sun, W.Y., P.C., D.M., W.L., H.T., Z.H., Y.X., J.H., Xiaomin Wang, L.G., C.Z., G.Y.), Central South University, Changsha, China.
  • Zeng G; Department of Cardiology, Third Hospital of Changsha, China (Y.Z.).
  • Zeng J; Department of Cardiology, Shaoyang Central Hospital, China (Z.O., X. Shi).
  • Dai H; Department of Cardiology, Shaoyang Central Hospital, China (Z.O., X. Shi).
  • Peng J; Department of Cardiology, The First People's Hospital of Shaoyang, China (C.L., Z.P.).
  • Zhang Y; Department of Cardiology, The First People's Hospital of Shaoyang, China (C.L., Z.P.).
  • Xu F; Department of Vascular Surgery (G.X.), The Second Affiliated Hospital, University of South China, Hengyang.
  • Wu J; Department of Cardiology (G.Z.), The Second Affiliated Hospital, University of South China, Hengyang.
  • Chen X; Department of Cardiology, Xiangtan Central Hospital, China (J.Z.).
  • Gong H; Department of Cardiology, Changsha Central Hospital, China (H.D.).
  • Yang Z; Department of Cardiology, Hunan Provincial People's Hospital, China (Jianqiang Peng).
  • Wu X; Department of Cardiology, Third Hospital of Changsha, China (Y.Z.).
  • Fang Q; Department of Cardiology, First People's Hospital of Xiangtan City, China (F.X.).
  • Yang L; Department of Cardiology, First Affiliated Hospital of University of South China, Hengyang (J.W.).
  • Li H; Department of Cardiology, Chenzhou First People's Hospital, China (Xiaoliang Chen).
  • Tan H; Department of Cardiology, The Fourth Hospital of Changsha, China (H.G.).
  • Huang Z; Department of Cardiology, Loudi Central Hospital, China (Z. Yang).
  • Tang X; Department of Cardiology, Yiyang Central Hospital, China (X. Wu).
  • Yang Q; School of Mathematics and Statistics (Q.F., L.Y.), Central South University, Changsha, China.
  • Tu S; School of Mathematics and Statistics (Q.F., L.Y.), Central South University, Changsha, China.
  • Wang X; Department of Pharmacy, Changsha Medical University, China (H.L.).
  • Xiang Y; Center of Clinical Pharmacology, the Third Xiangya Hospital (C.G., Y.K., H.Y., J.Y., X. Sun, W.Y., P.C., D.M., W.L., H.T., Z.H., Y.X., J.H., Xiaomin Wang, L.G., C.Z., G.Y.), Central South University, Changsha, China.
  • Huang J; Center of Clinical Pharmacology, the Third Xiangya Hospital (C.G., Y.K., H.Y., J.Y., X. Sun, W.Y., P.C., D.M., W.L., H.T., Z.H., Y.X., J.H., Xiaomin Wang, L.G., C.Z., G.Y.), Central South University, Changsha, China.
  • Wang X; Department of Cardiology, The Third Xiangya Hospital (J.L., W.J., X.T., Q.Y., S.T., Xiaoyan Wang, J.C., S.J.), Central South University, Changsha, China.
  • Cai J; Department of Cardiology, The Third Xiangya Hospital (J.L., W.J., X.T., Q.Y., S.T., Xiaoyan Wang, J.C., S.J.), Central South University, Changsha, China.
  • Jiang S; Department of Cardiology, The Third Xiangya Hospital (J.L., W.J., X.T., Q.Y., S.T., Xiaoyan Wang, J.C., S.J.), Central South University, Changsha, China.
  • Huang L; Department of Cardiology, The Third Xiangya Hospital (J.L., W.J., X.T., Q.Y., S.T., Xiaoyan Wang, J.C., S.J.), Central South University, Changsha, China.
Circ Genom Precis Med ; 13(4): e002602, 2020 08.
Article in En | MEDLINE | ID: mdl-32510984
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Atrial Fibrillation / Warfarin / Venous Thrombosis / Asian People / Anticoagulants Type of study: Clinical_trials / Etiology_studies / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Circ Genom Precis Med Year: 2020 Document type: Article Affiliation country: China Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Atrial Fibrillation / Warfarin / Venous Thrombosis / Asian People / Anticoagulants Type of study: Clinical_trials / Etiology_studies / Prognostic_studies Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Circ Genom Precis Med Year: 2020 Document type: Article Affiliation country: China Country of publication: United States