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May VelScope Be Deemed an Opportunistic Oral Cancer Screening by General Dentists? A Pilot Study.
Leuci, Stefania; Coppola, Noemi; Turkina, Anna; Bizzoca, Maria Eleonora; Favia, Gianfranco; Spagnuolo, Gianrico; Mignogna, Michele Davide.
Affiliation
  • Leuci S; Department of Neurosciences, Reproductive and Odontostomatological Sciences, Oral Medicine Unit, Federico II University of Naples, 80131 Naples, Italy.
  • Coppola N; Department of Neurosciences, Reproductive and Odontostomatological Sciences, Oral Medicine Unit, Federico II University of Naples, 80131 Naples, Italy.
  • Turkina A; Department of Therapeuthic Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
  • Bizzoca ME; Department of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.
  • Favia G; Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70121 Bari, Italy.
  • Spagnuolo G; Department of Neurosciences, Reproductive and Odontostomatological Sciences, Oral Medicine Unit, Federico II University of Naples, 80131 Naples, Italy.
  • Mignogna MD; Department of Therapeuthic Dentistry, I.M. Sechenov First Moscow State Medical University (Sechenov University), 119991 Moscow, Russia.
J Clin Med ; 9(6)2020 Jun 05.
Article in En | MEDLINE | ID: mdl-32516953
Early diagnosis of oral cancer through visual inspection followed by histopathological confirmation is a pivotal step for reducing rates of morbidity and mortality. There are several auxiliary devices used to improve oral examination. The purpose of this cross-sectional pilot study is to evaluate the sensitivity and specificity of the Visually Enhance Lesion Scope (VelScope) system when it is used by the general dentist after a yearly oral medicine training. Thirty-five patients with oral lesions were evaluated with clinical and VelScope examination by two general dentists, one of which trained with a specific course. A comparison of the histopathological results, clinical examination, and VelScope made by both dentists was performed through statistical analysis. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for detecting oral potentially malignant disorders (OPMDs) are 53.3%, 65%, 53.3%, 76.5% for unskilled dentist, 73.3%, 65%, 61.1%, 76.5% for skilled clinician. When both examiners use VelScope the values are 53.3%, 70%, 57.1%, 66.7% for unskilled general dentist (u-GD), 86.7%, 90%, 86.7%, 90% for skilled general dentist (s-GD). Improvement of a skilled general dentist for detecting malignancies is higher than inexperienced examiner when using VelScope. VelScope alone is unable to improve the general dentist's ability to detect malignancies, but it could be a useful adjunctive device for clinicians when a focused training program is performed.
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Screening_studies Language: En Journal: J Clin Med Year: 2020 Document type: Article Affiliation country: Italy Country of publication: Switzerland

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies / Screening_studies Language: En Journal: J Clin Med Year: 2020 Document type: Article Affiliation country: Italy Country of publication: Switzerland