Effects of intravenous and oral di(2-ethylhexyl) phthalate (DEHP) and 20% Intralipid vehicle on neonatal rat testis, lung, liver, and kidney.

Camacho, Luísa; Latendresse, John R; Muskhelishvili, Levan; Law, Charles D; Delclos, K Barry

Camacho, Luísa; Latendresse, John R; Muskhelishvili, Levan; Law, Charles D; Delclos, K Barry.

Affiliation

Camacho L; Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Latendresse JR; Toxicologic Pathology Associates, Jefferson, AR, 72079, USA.
Muskhelishvili L; Toxicologic Pathology Associates, Jefferson, AR, 72079, USA.
Law CD; Division of Neurotoxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA.
Delclos KB; Division of Biochemical Toxicology, National Center for Toxicological Research, Jefferson, AR, 72079, USA. Electronic address: barry.delclos@fda.hhs.gov.

Food Chem Toxicol ; 144: 111497, 2020 Oct.

Article in En | MEDLINE | ID: mdl-32540476

Subject(s)

Diethylhexyl Phthalate/toxicity; Kidney/drug effects; Liver/drug effects; Lung/drug effects; Testis/drug effects; Administration, Oral; Animals; Animals, Newborn; Body Weight/drug effects; Diethylhexyl Phthalate/administration & dosage; Dose-Response Relationship, Drug; Granuloma/chemically induced; Injections, Intravenous; Male; No-Observed-Adverse-Effect Level; Organ Size/drug effects; Rats; Rats, Sprague-Dawley

Key words

DEHP; Developmental exposure; Intralipid; Lung toxicity; Reproductive toxicity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Testis / Diethylhexyl Phthalate / Kidney / Liver / Lung Limits: Animals Language: En Journal: Food Chem Toxicol Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom

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