Regenerative potential of Wharton's jelly-derived mesenchymal stem cells: A new horizon of stem cell therapy.
J Cell Physiol
; 235(12): 9230-9240, 2020 12.
Article
in En
| MEDLINE
| ID: mdl-32557631
ABSTRACT
Umbilical cord Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) have recently gained considerable attention in the field of regenerative medicine. Their high proliferation rate, differentiation ability into various cell lineages, easy collection procedure, immuno-privileged status, nontumorigenic properties along with minor ethical issues make them an ideal approach for tissue repair. Besides, the number of WJ-MSCs in the umbilical cord samples is high as compared to other sources. Because of these properties, WJ-MSCs have rapidly advanced into clinical trials for the treatment of a wide range of disorders. Therefore, this paper summarized the current preclinical and clinical studies performed to investigate the regenerative potential of WJ-MSCs in neural, myocardial, skin, liver, kidney, cartilage, bone, muscle, and other tissue injuries.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Umbilical Cord
/
Stem Cell Transplantation
/
Wharton Jelly
/
Mesenchymal Stem Cells
Aspects:
Ethics
Limits:
Humans
Language:
En
Journal:
J Cell Physiol
Year:
2020
Document type:
Article
Affiliation country:
Iran