Nickel-catalyzed regio- and diastereoselective hydroarylative and hydroalkenylative cyclization of 1,6-dienes.
Chem Commun (Camb)
; 56(56): 7741-7744, 2020 Jul 18.
Article
in En
| MEDLINE
| ID: mdl-32558829
ABSTRACT
An unprecedented nickel-catalyzed hydroarylative and hydroalkenylative cyclization of unsymmetrically substituted 1,6-dienes with organoboronic acid was developed by using MeOH as the hydrogen source and employing commercially available Ni(η2-1,5-cyclooctadiene)2 as the catalyst. A series of biologically interesting cyclic products were afforded in moderate to excellent yields with high regio- and diastereoselectivities.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Language:
En
Journal:
Chem Commun (Camb)
Journal subject:
QUIMICA
Year:
2020
Document type:
Article
Affiliation country:
China