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A novel Cas9-targeted long-read assay for simultaneous detection of IDH1/2 mutations and clinically relevant MGMT methylation in fresh biopsies of diffuse glioma.
Wongsurawat, Thidathip; Jenjaroenpun, Piroon; De Loose, Annick; Alkam, Duah; Ussery, David W; Nookaew, Intawat; Leung, Yuet-Kin; Ho, Shuk-Mei; Day, John D; Rodriguez, Analiz.
Affiliation
  • Wongsurawat T; Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA. twongsurawat@uams.edu.
  • Jenjaroenpun P; Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • De Loose A; Department of Neurosurgery, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • Alkam D; Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • Ussery DW; Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • Nookaew I; Department of Biomedical Informatics, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • Leung YK; Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • Ho SM; Department of Pharmacology and Toxicology, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • Day JD; Department of Neurosurgery, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA.
  • Rodriguez A; Department of Neurosurgery, College of Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, 72205, USA. arodriguez@uams.edu.
Acta Neuropathol Commun ; 8(1): 87, 2020 06 20.
Article in En | MEDLINE | ID: mdl-32563269
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / DNA Modification Methylases / Sequence Analysis, RNA / Tumor Suppressor Proteins / DNA Repair Enzymes / CRISPR-Associated Protein 9 / Glioma / Isocitrate Dehydrogenase Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Acta Neuropathol Commun Year: 2020 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain Neoplasms / DNA Modification Methylases / Sequence Analysis, RNA / Tumor Suppressor Proteins / DNA Repair Enzymes / CRISPR-Associated Protein 9 / Glioma / Isocitrate Dehydrogenase Type of study: Diagnostic_studies / Prognostic_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Acta Neuropathol Commun Year: 2020 Document type: Article Affiliation country: United States