Progress toward Alzheimer's disease treatment: Leveraging the Achilles' heel of Aß oligomers?

Fantini, Jacques; Chahinian, Henri; Yahi, Nouara

Fantini, Jacques; Chahinian, Henri; Yahi, Nouara.

Affiliation

Fantini J; INSERM UMR_S 1072, Aix-Marseille Université, Marseille, France.
Chahinian H; INSERM UMR_S 1072, Aix-Marseille Université, Marseille, France.
Yahi N; INSERM UMR_S 1072, Aix-Marseille Université, Marseille, France.

Protein Sci ; 29(8): 1748-1759, 2020 08.

Article in En | MEDLINE | ID: mdl-32567070

Subject(s)

Alzheimer Disease; Antibodies, Monoclonal/therapeutic use; Brain; Neurons; Alzheimer Disease/drug therapy; Alzheimer Disease/metabolism; Alzheimer Disease/pathology; Amyloid beta-Peptides/antagonists & inhibitors; Amyloid beta-Peptides/metabolism; Animals; Brain/metabolism; Brain/pathology; Calcium/metabolism; Calcium Signaling/drug effects; Humans; Neurons/metabolism; Neurons/pathology

Key words

Alzheimer; Parkinson; amyloid pore; cholesterol; ganglioside; lipid raft; neurodegenerative disease; oligomer

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Brain / Alzheimer Disease / Antibodies, Monoclonal / Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Protein Sci Journal subject: BIOQUIMICA Year: 2020 Document type: Article Affiliation country: France Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google