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Discovery of Small Molecule Inhibitors of Huntingtin Exon 1 Aggregation by FRET-Based High-Throughput Screening in Living Cells.
Lo, Chih Hung; Pandey, Nitin K; Lim, Colin Kin-Wye; Ding, Zhipeng; Tao, Meixin; Thomas, David D; Langen, Ralf; Sachs, Jonathan N.
Affiliation
  • Lo CH; Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States.
  • Pandey NK; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
  • Lim CK; Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States.
  • Ding Z; Department of Biomedical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States.
  • Tao M; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
  • Thomas DD; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, Minnesota 55455, United States.
  • Langen R; Photonic Pharma LLC, Minneapolis, Minnesota 55410, United States.
  • Sachs JN; Department of Physiology and Neuroscience, Zilkha Neurogenetic Institute, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, United States.
ACS Chem Neurosci ; 11(15): 2286-2295, 2020 08 05.
Article in En | MEDLINE | ID: mdl-32568514
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Huntington Disease / Fluorescence Resonance Energy Transfer Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: ACS Chem Neurosci Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Huntington Disease / Fluorescence Resonance Energy Transfer Type of study: Diagnostic_studies / Screening_studies Limits: Humans Language: En Journal: ACS Chem Neurosci Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States