Maternal obesity increases offspring's mammary cancer recurrence and impairs tumor immune response.

Zhang, Xiyuan; de Oliveira Andrade, Fabia; Zhang, Hansheng; Cruz, Idalia; Clarke, Robert; Gaur, Pankaj; Verma, Vivek; Hilakivi-Clarke, Leena

Zhang, Xiyuan; de Oliveira Andrade, Fabia; Zhang, Hansheng; Cruz, Idalia; Clarke, Robert; Gaur, Pankaj; Verma, Vivek; Hilakivi-Clarke, Leena.

Affiliation

Clarke R; Department of Oncology, Georgetown University, Washington, District of Columbia, USA.
Gaur P; Department of Oncology, Georgetown University, Washington, District of Columbia, USA.
Verma V; Department of Oncology, Georgetown University, Washington, District of Columbia, USA.
Hilakivi-Clarke L; Department of Oncology, Georgetown University, Washington, District of Columbia, USA.

Endocr Relat Cancer ; 27(9): 469-482, 2020 09.

Article in En | MEDLINE | ID: mdl-32580156

Subject(s)

Breast Neoplasms/genetics; Immunity/genetics; Obesity, Maternal/complications; Animals; Breast Neoplasms/physiopathology; Female; Humans; Neoplasm Recurrence, Local; Obesity, Maternal/pathology; Pregnancy; Rats, Sprague-Dawley

Key words

breast cancer; inflammation; local recurrence; tamoxifen therapy; tumor immune microenvironment

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Obesity, Maternal / Immunity Limits: Animals / Female / Humans / Pregnancy Language: En Journal: Endocr Relat Cancer Journal subject: ENDOCRINOLOGIA / NEOPLASIAS Year: 2020 Document type: Article Country of publication: United kingdom

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