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KRASQ61H Preferentially Signals through MAPK in a RAF Dimer-Dependent Manner in Non-Small Cell Lung Cancer.
Zhou, Zhi-Wei; Ambrogio, Chiara; Bera, Asim K; Li, Qing; Li, Xing-Xiao; Li, Lianbo; Son, Jieun; Gondi, Sudershan; Li, Jiaqi; Campbell, Emily; Jin, Hua; Okoro, Jeffrey J; Xu, Cheng-Xiong; Janne, Pasi A; Westover, Kenneth D.
Affiliation
  • Zhou ZW; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
  • Ambrogio C; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Bera AK; Department of Molecular Biotechnology and Health Science, Molecular Biotechnology Center, University of Torino, Torino, Italy.
  • Li Q; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
  • Li XX; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
  • Li L; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
  • Son J; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
  • Gondi S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Li J; Departments of Biochemistry and Radiation Oncology, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas.
  • Campbell E; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Jin H; Department of Physiology and Developmental Biology, Brigham Young University, Provo, Utah.
  • Okoro JJ; Department of Thoracic Surgery, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China.
  • Xu CX; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.
  • Janne PA; Cancer Center, Daping Hospital and Research Institute of Surgery, Third Military Medical University, Chongqing, China. kenneth.westover@utsouthwestern.edu pasi_janne@dfci.harvard.edu xuchengxiong@hanmail.net.
  • Westover KD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. kenneth.westover@utsouthwestern.edu pasi_janne@dfci.harvard.edu xuchengxiong@hanmail.net.
Cancer Res ; 80(17): 3719-3731, 2020 09 01.
Article in En | MEDLINE | ID: mdl-32605999
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins p21(ras) / Carcinoma, Non-Small-Cell Lung / MAP Kinase Signaling System / Raf Kinases / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2020 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proto-Oncogene Proteins p21(ras) / Carcinoma, Non-Small-Cell Lung / MAP Kinase Signaling System / Raf Kinases / Lung Neoplasms Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: Cancer Res Year: 2020 Document type: Article Country of publication: United States