Evolocumab, a PCSK9 inhibitor, protects human endothelial cells against H<sub>2</sub>O<sub>2</sub>-induced oxidative stress.

Safaeian, Leila; Mirian, Mina; Bahrizadeh, Shahryar

Evolocumab, a PCSK9 inhibitor, protects human endothelial cells against H₂O₂-induced oxidative stress.

Safaeian, Leila; Mirian, Mina; Bahrizadeh, Shahryar.

Affiliation

Safaeian L; Department of Pharmacology and Toxicology, Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
Mirian M; Department of Pharmaceutical Biotechnology, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
Bahrizadeh S; Department of Pharmacology and Toxicology, Isfahan Pharmaceutical Sciences Research Center, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.

Arch Physiol Biochem ; 128(6): 1681-1686, 2022 Dec.

Article in En | MEDLINE | ID: mdl-32619370

Subject(s)

Antioxidants; Hydrogen Peroxide; Humans; Hydrogen Peroxide/toxicity; Antioxidants/pharmacology; Oxidative Stress; Human Umbilical Vein Endothelial Cells; Malondialdehyde; Subtilisins/pharmacology; Proprotein Convertase 9/pharmacology

Key words

Antioxidants; HUVEC; cell viability; evolocumab; oxidative stress

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Hydrogen Peroxide / Antioxidants Limits: Humans Language: En Journal: Arch Physiol Biochem Journal subject: BIOQUIMICA / FISIOLOGIA Year: 2022 Document type: Article Affiliation country: Iran Country of publication: United kingdom

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