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Neutrophil elastase triggers the development of autoimmune diabetes by exacerbating innate immune responses in pancreatic islets of non-obese diabetic mice.
Shu, Lingling; Zhong, Ling; Xiao, Yang; Wu, Xiaoping; Liu, Yang; Jiang, Xue; Tang, Tao; Hoo, RubyLaiChong; Zhou, Zhiguang; Xu, Aimin.
Affiliation
  • Shu L; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, China.
  • Zhong L; Department of Hematology Oncology, Cancer Center, Sun Yat-Sen University, Guangzhou, Guangdong, China.
  • Xiao Y; Department of Medicine, The University of Hong Kong, Hong Kong, China.
  • Wu X; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, China.
  • Liu Y; Department of Medicine, The University of Hong Kong, Hong Kong, China.
  • Jiang X; Second Xiangya Hospital, Key Laboratory of Diabetes Immunology, Central South University, National Clinical Research Center for Metabolic Diseases, Changsha, China.
  • Tang T; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, China.
  • Hoo R; Department of Pharmacology and Pharmacy, The University of Hong Kong, China.
  • Zhou Z; Department of Neurosurgery, Zhujiang Hospital, Southern Medical University, China.
  • Xu A; State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, China.
Clin Sci (Lond) ; 134(13): 1679-1696, 2020 07 17.
Article in En | MEDLINE | ID: mdl-32633320

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Islets of Langerhans / Leukocyte Elastase / Diabetes Mellitus, Type 1 Limits: Animals / Female / Humans Language: En Journal: Clin Sci (Lond) Year: 2020 Document type: Article Affiliation country: China Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Islets of Langerhans / Leukocyte Elastase / Diabetes Mellitus, Type 1 Limits: Animals / Female / Humans Language: En Journal: Clin Sci (Lond) Year: 2020 Document type: Article Affiliation country: China Country of publication: United kingdom