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USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Rusilowicz-Jones, Emma V; Jardine, Jane; Kallinos, Andreas; Pinto-Fernandez, Adan; Guenther, Franziska; Giurrandino, Mariacarmela; Barone, Francesco G; McCarron, Katy; Burke, Christopher J; Murad, Alejandro; Martinez, Aitor; Marcassa, Elena; Gersch, Malte; Buckmelter, Alexandre J; Kayser-Bricker, Katherine J; Lamoliatte, Frederic; Gajbhiye, Akshada; Davis, Simon; Scott, Hannah C; Murphy, Emma; England, Katherine; Mortiboys, Heather; Komander, David; Trost, Matthias; Kessler, Benedikt M; Ioannidis, Stephanos; Ahlijanian, Michael K; Urbé, Sylvie; Clague, Michael J.
Affiliation
  • Rusilowicz-Jones EV; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Jardine J; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Kallinos A; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Pinto-Fernandez A; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Guenther F; Alzheimer's Research UK, Oxford Drug Discovery Institute, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Giurrandino M; Alzheimer's Research UK, Oxford Drug Discovery Institute, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Barone FG; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • McCarron K; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Burke CJ; FORMA Therapeutics, Watertown, MA, USA.
  • Murad A; FORMA Therapeutics, Watertown, MA, USA.
  • Martinez A; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Marcassa E; Department of Cellular and Molecular Physiology, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.
  • Gersch M; Chemical Genomics Centre, Max-Planck-Institute of Molecular Physiology, Dortmund, Germany.
  • Buckmelter AJ; Department of Chemistry and Chemical Biology, Technische Universität Dortmund, Dortmund, Germany.
  • Kayser-Bricker KJ; FORMA Therapeutics, Watertown, MA, USA.
  • Lamoliatte F; FORMA Therapeutics, Watertown, MA, USA.
  • Gajbhiye A; Laboratory for Biological Mass Spectrometry, Newcastle University Biosciences Institute, Faculty of Medical Sciences, University of Newcastle, Newcastle, UK.
  • Davis S; Laboratory for Biological Mass Spectrometry, Newcastle University Biosciences Institute, Faculty of Medical Sciences, University of Newcastle, Newcastle, UK.
  • Scott HC; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Murphy E; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • England K; Alzheimer's Research UK, Oxford Drug Discovery Institute, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Mortiboys H; Alzheimer's Research UK, Oxford Drug Discovery Institute, Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Komander D; Sheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, UK.
  • Trost M; Ubiquitin Signalling Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Australia.
  • Kessler BM; Department of Medical Biology, University of Melbourne, Melbourne, Australia.
  • Ioannidis S; Laboratory for Biological Mass Spectrometry, Newcastle University Biosciences Institute, Faculty of Medical Sciences, University of Newcastle, Newcastle, UK.
  • Ahlijanian MK; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Urbé S; FORMA Therapeutics, Watertown, MA, USA.
  • Clague MJ; FORMA Therapeutics, Watertown, MA, USA.
Life Sci Alliance ; 3(8)2020 08.
Article in En | MEDLINE | ID: mdl-32636217
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiolester Hydrolases / Mitochondrial Proteins / Mitochondria Type of study: Prognostic_studies Limits: Humans Language: En Journal: Life Sci Alliance Year: 2020 Document type: Article Affiliation country: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiolester Hydrolases / Mitochondrial Proteins / Mitochondria Type of study: Prognostic_studies Limits: Humans Language: En Journal: Life Sci Alliance Year: 2020 Document type: Article Affiliation country: United kingdom