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Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature.
Akebo, Hiroyuki; Sada, Ryuichi; Matsushita, Sho; Ishimaru, Hiroyasu; Minoda, Saki; Miyake, Hirofumi; Tsugihashi, Yukio; Hatta, Kazuhiro.
Affiliation
  • Akebo H; Department of General Internal Medicine, Tenri Hospital, Japan.
  • Sada R; Department of General Internal Medicine, Tenri Hospital, Japan.
  • Matsushita S; Department of General Internal Medicine, Tenri Hospital, Japan.
  • Ishimaru H; Department of General Internal Medicine, Tenri Hospital, Japan.
  • Minoda S; Department of General Internal Medicine, Tenri Hospital, Japan.
  • Miyake H; Department of General Internal Medicine, Tenri Hospital, Japan.
  • Tsugihashi Y; Department of Health Care, Tenri Health Care University, Japan.
  • Hatta K; Department of General Internal Medicine, Tenri Hospital, Japan.
Intern Med ; 59(21): 2789-2795, 2020 Nov 01.
Article in En | MEDLINE | ID: mdl-32641654
ABSTRACT
Lupus aortitis is a rare and potentially life-threatening disorder. Previous studies have reported the utility of high-dose systemic glucocorticoids or surgery as the treatment, although there have been no related controlled trials. We herein report a 49-year-old woman with a 35-year history of systemic lupus erythematosus who was diagnosed with aortitis. Her symptoms and laboratory and imaging abnormalities rapidly resolved upon the administration of moderate-dose glucocorticoids. We subsequently performed a literature review of similar cases to identify the appropriate treatment and discuss these cases. A study of further cases will be needed to identify the characteristics of patients who would benefit from moderate-dose glucocorticoid therapy.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortitis / Dose-Response Relationship, Drug / Glucocorticoids / Lupus Erythematosus, Systemic Type of study: Diagnostic_studies / Prognostic_studies Limits: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Language: En Journal: Intern Med Journal subject: MEDICINA INTERNA Year: 2020 Document type: Article Affiliation country: Japan

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortitis / Dose-Response Relationship, Drug / Glucocorticoids / Lupus Erythematosus, Systemic Type of study: Diagnostic_studies / Prognostic_studies Limits: Adolescent / Adult / Aged / Aged80 / Child / Female / Humans / Male / Middle aged Language: En Journal: Intern Med Journal subject: MEDICINA INTERNA Year: 2020 Document type: Article Affiliation country: Japan
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