Development of depression in patients with oral cavity cancer: a systematic review.
Acta Otolaryngol
; 140(10): 876-881, 2020 Oct.
Article
in En
| MEDLINE
| ID: mdl-32644847
ABSTRACT
BACKGROUND:
The incidence of oral cancer is approximately 300,000 patients annually. A cancer diagnosis and treatment affect both physical and mental issues.OBJECTIVES:
The aim of this systematic review was to examine the development of depression in patients who have been treated for oral squamous cell carcinoma (OSCC). MATERIAL ANDMETHODS:
PubMed and EMBASE were systematically searched for studies addressing depression among patients treated for OSCC and published within the past ten years.RESULTS:
We identified three studies comprising 528 patients (range 75-349), primarily men (66-83%), treated for OSCC from Europe and India. Tumour stage, treatment modality, and scales used to evaluate depressive symptoms varied in the studies. The European studies showed that 28% of the patients experienced depressive symptoms on the Hospital Anxiety and Depression Scale (HADS) and a mean of 8.0 on depression in the Brief Symptom Inventory (BSI). The Indian study showed a significant increase (p Value < .001) from moderate to severe depressive symptoms on the Depression, Anxiety, and Stress Scale-21 (DASS-21).Conclusion andSignificance:
This systematic review showed that OSCC patients are at risk of developing depressive symptoms after treatment, though severity of symptoms varied. This knowledge could preferably be implemented in future follow-up regimes.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Mouth Neoplasms
/
Depression
Type of study:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Systematic_reviews
Limits:
Humans
Language:
En
Journal:
Acta Otolaryngol
Year:
2020
Document type:
Article
Affiliation country:
Denmark