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Formaldehyde treatment of proteins enhances proteolytic degradation by the endo-lysosomal protease cathepsin S.
Michiels, Thomas J M; Meiring, Hugo D; Jiskoot, Wim; Kersten, Gideon F A; Metz, Bernard.
Affiliation
  • Michiels TJM; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, 2333 CC, Leiden, The Netherlands.
  • Meiring HD; Intravacc, Institute for Translational Vaccinology, 3721 MA, Bilthoven, The Netherlands.
  • Jiskoot W; Intravacc, Institute for Translational Vaccinology, 3721 MA, Bilthoven, The Netherlands.
  • Kersten GFA; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, 2333 CC, Leiden, The Netherlands.
  • Metz B; Division of BioTherapeutics, Leiden Academic Centre for Drug Research (LACDR), Leiden University, 2333 CC, Leiden, The Netherlands.
Sci Rep ; 10(1): 11535, 2020 07 14.
Article in En | MEDLINE | ID: mdl-32665578
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endosomes / Cathepsins / Formaldehyde / Lysosomes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endosomes / Cathepsins / Formaldehyde / Lysosomes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom