Redefining Cardiac Biomarkers in Predicting Mortality of Inpatients With COVID-19.

Qin, Juan-Juan; Cheng, Xu; Zhou, Feng; Lei, Fang; Akolkar, Gauri; Cai, Jingjing; Zhang, Xiao-Jing; Blet, Alice; Xie, Jing; Zhang, Peng; Liu, Ye-Mao; Huang, Zizhen; Zhao, Ling-Ping; Lin, Lijin; Xia, Meng; Chen, Ming-Ming; Song, Xiaohui; Bai, Liangjie; Chen, Ze; Zhang, Xingyuan; Xiang, Da; Chen, Jing; Xu, Qingbo; Ma, Xinliang; Touyz, Rhian M; Gao, Chen; Wang, Haitao; Liu, Liming; Mao, Weiming; Luo, Pengcheng; Yan, Youqin; Ye, Ping; Chen, Manhua; Chen, Guohua; Zhu, Lihua; She, Zhi-Gang; Huang, Xiaodong; Yuan, Yufeng; Zhang, Bing-Hong; Wang, Yibin; Liu, Peter P; Li, Hongliang

Qin, Juan-Juan; Cheng, Xu; Zhou, Feng; Lei, Fang; Akolkar, Gauri; Cai, Jingjing; Zhang, Xiao-Jing; Blet, Alice; Xie, Jing; Zhang, Peng; Liu, Ye-Mao; Huang, Zizhen; Zhao, Ling-Ping; Lin, Lijin; Xia, Meng; Chen, Ming-Ming; Song, Xiaohui; Bai, Liangjie; Chen, Ze; Zhang, Xingyuan; Xiang, Da; Chen, Jing; Xu, Qingbo; Ma, Xinliang; Touyz, Rhian M; Gao, Chen; Wang, Haitao; Liu, Liming; Mao, Weiming; Luo, Pengcheng; Yan, Youqin; Ye, Ping; Chen, Manhua; Chen, Guohua; Zhu, Lihua; She, Zhi-Gang; Huang, Xiaodong; Yuan, Yufeng; Zhang, Bing-Hong; Wang, Yibin; Liu, Peter P; Li, Hongliang.

Affiliation

Qin JJ; From the Department of Cardiology (J.-J.Q.), Zhongnan Hospital of Wuhan University, China.
Cheng X; Department of Cardiology (J.-J.Q., X.C., X.-J.Z., J.X., Y.-M.L., L.L., M.-M.C., L.Z., Z.-G.S., H.L.), Renmin Hospital of Wuhan University, China.
Zhou F; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Lei F; Department of Cardiology (J.-J.Q., X.C., X.-J.Z., J.X., Y.-M.L., L.L., M.-M.C., L.Z., Z.-G.S., H.L.), Renmin Hospital of Wuhan University, China.
Akolkar G; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Cai J; Medical Science Research Center (F.Z., P.Z., H.L.), Zhongnan Hospital of Wuhan University, China.
Zhang XJ; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Blet A; Basic Medical School, Wuhan University, China (F.L., Z.H., X.S., Z.C., X.Z., H.L.).
Xie J; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Zhang P; Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ontario, Canada (G.A., A.B., P.P.L.).
Huang Z; Department of Cardiology (J.-J.Q., X.C., X.-J.Z., J.X., Y.-M.L., L.L., M.-M.C., L.Z., Z.-G.S., H.L.), Renmin Hospital of Wuhan University, China.
Zhao LP; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Lin L; Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ontario, Canada (G.A., A.B., P.P.L.).
Xia M; Department of Cardiology (J.-J.Q., X.C., X.-J.Z., J.X., Y.-M.L., L.L., M.-M.C., L.Z., Z.-G.S., H.L.), Renmin Hospital of Wuhan University, China.
Chen MM; Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ontario, Canada (G.A., A.B., P.P.L.).
Song X; Medical Science Research Center (F.Z., P.Z., H.L.), Zhongnan Hospital of Wuhan University, China.
Bai L; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Chen Z; Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ontario, Canada (G.A., A.B., P.P.L.).
Zhang X; Department of Cardiology (J.-J.Q., X.C., X.-J.Z., J.X., Y.-M.L., L.L., M.-M.C., L.Z., Z.-G.S., H.L.), Renmin Hospital of Wuhan University, China.
Xiang D; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Chen J; Basic Medical School, Wuhan University, China (F.L., Z.H., X.S., Z.C., X.Z., H.L.).
Xu Q; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Ma X; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Touyz RM; Department of Cardiology (J.-J.Q., X.C., X.-J.Z., J.X., Y.-M.L., L.L., M.-M.C., L.Z., Z.-G.S., H.L.), Renmin Hospital of Wuhan University, China.
Gao C; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Wang H; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Liu L; Department of Cardiology (J.-J.Q., X.C., X.-J.Z., J.X., Y.-M.L., L.L., M.-M.C., L.Z., Z.-G.S., H.L.), Renmin Hospital of Wuhan University, China.
Mao W; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Luo P; Basic Medical School, Wuhan University, China (F.L., Z.H., X.S., Z.C., X.Z., H.L.).
Yan Y; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Ye P; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Chen M; Basic Medical School, Wuhan University, China (F.L., Z.H., X.S., Z.C., X.Z., H.L.).
Chen G; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Zhu L; Basic Medical School, Wuhan University, China (F.L., Z.H., X.S., Z.C., X.Z., H.L.).
She ZG; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Huang X; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Yuan Y; Institute of Model Animal of Wuhan University, China (J.-J.Q., X.C., F.Z., F.L., X.-J.Z., P.Z., Y.-M.L., Z.H., L.-P.Z., L.L., M.X., M.-M.C., X.S., L.B., Z.C., X.Z., D.X., J. Chen, L.Z., Z.-G.S., H.L.).
Zhang BH; Centre for Clinic Pharmacology, The William Harvey Research Institute, Queen Mary University of London, United Kingdom (Q.X.).
Wang Y; Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, Pennsylvania (X.M.).
Liu PP; Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, United Kingdom (R.M.T.).
Li H; Department of Anesthesiology, Cardiovascular Research Laboratories, David Geffen School of Medicine, University of California, Los Angeles (C.G., Y.W.).

Hypertension ; 76(4): 1104-1112, 2020 10.

Article in En | MEDLINE | ID: mdl-32673499

Subject(s)

Coronavirus Infections; Creatine Kinase, MB Form/blood; Heart Diseases; Natriuretic Peptide, Brain/blood; Pandemics; Peptide Fragments/blood; Pneumonia, Viral; Troponin I/blood; Betacoronavirus/isolation & purification; Biomarkers/blood; COVID-19; China/epidemiology; Coronavirus Infections/blood; Coronavirus Infections/mortality; Coronavirus Infections/therapy; Female; Heart Diseases/blood; Heart Diseases/mortality; Heart Diseases/virology; Hospitalization/statistics & numerical data; Humans; Male; Middle Aged; Mortality; Outcome Assessment, Health Care; Pneumonia, Viral/blood; Pneumonia, Viral/mortality; Pneumonia, Viral/therapy; Predictive Value of Tests; Prognosis; Retrospective Studies; SARS-CoV-2

Key words

biomarkers; heart diseases; heart injuries; mortality; prognosis

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Pneumonia, Viral / Coronavirus Infections / Troponin I / Natriuretic Peptide, Brain / Creatine Kinase, MB Form / Pandemics / Heart Diseases Type of study: Guideline / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Female / Humans / Male / Middle aged Country/Region as subject: Asia Language: En Journal: Hypertension Year: 2020 Document type: Article Affiliation country: China Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google