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Pyrazolo[4,3-d]pyrimidine Derivatives as a Novel Hypoxia-Inducible Factor Prolyl Hydroxylase Domain Inhibitor for the Treatment of Anemia.
Goi, Takashi; Nakajima, Tatsuo; Komatsu, Yoshiyuki; Kawata, Atsushi; Yamakoshi, Shuhei; Okada, Okimasa; Sugahara, Masakatsu; Umeda, Asami; Takada, Yoko; Murakami, Jun; Ohashi, Rikiya; Watanabe, Tomoko; Fukase, Koichi.
Affiliation
  • Goi T; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
  • Nakajima T; Department of Chemistry, Graduate School of Science, Osaka University, 1-1, Machikaneyama, Toyonaka 560-0043, Japan.
  • Komatsu Y; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
  • Kawata A; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
  • Yamakoshi S; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
  • Okada O; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
  • Sugahara M; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
  • Umeda A; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
  • Takada Y; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
  • Murakami J; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
  • Ohashi R; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
  • Watanabe T; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
  • Fukase K; Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma Corporation, 1000, Kamoshida-cho, Aobaku, Yokohama 227-0033, Japan.
ACS Med Chem Lett ; 11(7): 1416-1420, 2020 Jul 09.
Article in En | MEDLINE | ID: mdl-32676148
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: ACS Med Chem Lett Year: 2020 Document type: Article Affiliation country: Japan Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: ACS Med Chem Lett Year: 2020 Document type: Article Affiliation country: Japan Country of publication: United States