Effects of age and sex on the relationship between body fat area and kidney events in patients with chronic kidney disease.
Ther Apher Dial
; 25(3): 290-295, 2021 Jun.
Article
in En
| MEDLINE
| ID: mdl-32681687
ABSTRACT
We examined the effects of age and sex on the relationship between body fat area and kidney events. We included 367 chronic kidney disease patients between 2011 and 2017. Patients' median age was 73.0 years; 262 (71.4%) patients were male. The median estimated glomerular filtration rate was 20.2 mL/min/1.73 m2 . During the observation period, 187 patients developed kidney events. In males aged <75 years, high subcutaneous fat area was a risk factor for kidney events (hazard ratio 1.06, 95% CI 1.02-1.11). In females aged <75 years, high visceral fat area reduced kidney events (hazard ratio 0.83, 95% CI 0.71-0.97). In males and females ≥75 years, visceral fat area and subcutaneous fat area were not associated with kidney events. Body fat area was not a risk factor for chronic kidney disease progression in elderly patients. Opposite effects, in sex-related body fat and kidney events, were shown in young patients.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Intra-Abdominal Fat
/
Subcutaneous Fat
/
Renal Insufficiency, Chronic
Type of study:
Etiology_studies
/
Observational_studies
/
Risk_factors_studies
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Language:
En
Journal:
Ther Apher Dial
Journal subject:
HEMATOLOGIA
Year:
2021
Document type:
Article
Affiliation country:
Japan
Publication country:
AU
/
AUSTRALIA
/
AUSTRÁLIA