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Subcutaneous administration of benzathine benzylpenicillin G has favourable pharmacokinetic characteristics for the prevention of rheumatic heart disease compared with intramuscular injection: a randomized, crossover, population pharmacokinetic study in healthy adult volunteers.
Kado, Joseph H; Salman, Sam; Henderson, Robert; Hand, Robert; Wyber, Rosemary; Page-Sharp, Madhu; Batty, Kevin; Carapetis, Jonathan; Manning, Laurens.
Affiliation
  • Kado JH; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia.
  • Salman S; Faculty of Health and Medical Sciences, University of Western Australia, Perth, Western Australia, Australia.
  • Henderson R; Faculty of Health and Medical Sciences, University of Western Australia, Perth, Western Australia, Australia.
  • Hand R; Department of Radiology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia.
  • Wyber R; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia.
  • Page-Sharp M; Wesfarmers Centre of Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia.
  • Batty K; The George Institute of Global Health, University of Sydney, Sydney, New South Wales, Australia.
  • Carapetis J; School of Pharmacy and Biomedical Sciences, Curtin University, Bentley, Western Australia, Australia.
  • Manning L; School of Pharmacy and Biomedical Sciences, Curtin University, Bentley, Western Australia, Australia.
J Antimicrob Chemother ; 75(10): 2951-2959, 2020 10 01.
Article in En | MEDLINE | ID: mdl-32696033
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Penicillin G Benzathine / Rheumatic Heart Disease Type of study: Clinical_trials / Guideline Limits: Adult / Humans / Male Language: En Journal: J Antimicrob Chemother Year: 2020 Document type: Article Affiliation country: Australia Country of publication: United kingdom
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Penicillin G Benzathine / Rheumatic Heart Disease Type of study: Clinical_trials / Guideline Limits: Adult / Humans / Male Language: En Journal: J Antimicrob Chemother Year: 2020 Document type: Article Affiliation country: Australia Country of publication: United kingdom