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Randomised clinical trial: significant biochemical and colonic transit effects of the farnesoid X receptor agonist tropifexor in patients with primary bile acid diarrhoea.
Camilleri, Michael; Nord, Sara Linker; Burton, Duane; Oduyebo, Ibironke; Zhang, Yiming; Chen, Jin; Im, Koeun; Bhad, Prafulla; Badman, Michael K; Sanders, David S; Walters, Julian R F.
Affiliation
  • Camilleri M; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Nord SL; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Burton D; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Oduyebo I; Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
  • Zhang Y; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Chen J; Novartis Pharmaceutical Corporation, East Hanover, NJ, USA.
  • Im K; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Bhad P; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Badman MK; Novartis Institutes for Biomedical Research, Cambridge, MA, USA.
  • Sanders DS; The Academic Unit of Gastroenterology, Royal Hallamshire Hospital, Sheffield, UK.
  • Walters JRF; Division of Digestive Diseases, Imperial College London, London, UK.
Aliment Pharmacol Ther ; 52(5): 808-820, 2020 09.
Article in En | MEDLINE | ID: mdl-32702169

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gastrointestinal Transit / Receptors, Cytoplasmic and Nuclear / Diarrhea / Benzothiazoles / Isoxazoles Type of study: Clinical_trials / Etiology_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Aliment Pharmacol Ther Journal subject: FARMACOLOGIA / GASTROENTEROLOGIA / TERAPIA POR MEDICAMENTOS Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gastrointestinal Transit / Receptors, Cytoplasmic and Nuclear / Diarrhea / Benzothiazoles / Isoxazoles Type of study: Clinical_trials / Etiology_studies Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Aliment Pharmacol Ther Journal subject: FARMACOLOGIA / GASTROENTEROLOGIA / TERAPIA POR MEDICAMENTOS Year: 2020 Document type: Article Affiliation country: United States Country of publication: United kingdom