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Inhibition of pyruvate dehydrogenase kinase­1 by dicoumarol enhances the sensitivity of hepatocellular carcinoma cells to oxaliplatin via metabolic reprogramming.
Xu, Huadan; He, Yichun; Ma, Jiaoyan; Zhao, Yuanxin; Liu, Yanan; Sun, Liankun; Su, Jing.
Affiliation
  • Xu H; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, P.R. China.
  • He Y; Department of Neurosurgery, China­Japan Union Hospital, Jilin University, Changchun, Jilin 130021, P.R. China.
  • Ma J; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, P.R. China.
  • Zhao Y; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, P.R. China.
  • Liu Y; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, P.R. China.
  • Sun L; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, P.R. China.
  • Su J; Key Laboratory of Pathobiology, Ministry of Education, Department of Pathophysiology, College of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, P.R. China.
Int J Oncol ; 57(3): 733-742, 2020 09.
Article in En | MEDLINE | ID: mdl-32705170
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dicumarol / Carcinoma, Hepatocellular / Drug Resistance, Neoplasm / Pyruvate Dehydrogenase Acetyl-Transferring Kinase / Liver Neoplasms Type of study: Diagnostic_studies Limits: Animals / Humans / Male Language: En Journal: Int J Oncol Journal subject: NEOPLASIAS Year: 2020 Document type: Article Country of publication: Greece
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dicumarol / Carcinoma, Hepatocellular / Drug Resistance, Neoplasm / Pyruvate Dehydrogenase Acetyl-Transferring Kinase / Liver Neoplasms Type of study: Diagnostic_studies Limits: Animals / Humans / Male Language: En Journal: Int J Oncol Journal subject: NEOPLASIAS Year: 2020 Document type: Article Country of publication: Greece