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A natural flavonoid, apigenin isolated from Clerodendrum viscosum leaves, induces G2/M phase cell cycle arrest and apoptosis in MCF-7 cells through the regulation of p53 and caspase-cascade pathway.
Shendge, A K; Chaudhuri, D; Basu, T; Mandal, N.
Affiliation
  • Shendge AK; Division of Molecular Medicine, Bose Institute, P-1/12 CIT Scheme - VIIM, Kolkata, West Bengal, 700054, India.
  • Chaudhuri D; Division of Molecular Medicine, Bose Institute, P-1/12 CIT Scheme - VIIM, Kolkata, West Bengal, 700054, India.
  • Basu T; Division of Molecular Medicine, Bose Institute, P-1/12 CIT Scheme - VIIM, Kolkata, West Bengal, 700054, India.
  • Mandal N; Division of Molecular Medicine, Bose Institute, P-1/12 CIT Scheme - VIIM, Kolkata, West Bengal, 700054, India. mandaln@rediffmail.com.
Clin Transl Oncol ; 23(4): 718-730, 2021 Apr.
Article in En | MEDLINE | ID: mdl-32715386

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Tumor Suppressor Protein p53 / Caspases / Apigenin / Antineoplastic Agents, Phytogenic Limits: Female / Humans Language: En Journal: Clin Transl Oncol Year: 2021 Document type: Article Affiliation country: India Country of publication: Italy

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Tumor Suppressor Protein p53 / Caspases / Apigenin / Antineoplastic Agents, Phytogenic Limits: Female / Humans Language: En Journal: Clin Transl Oncol Year: 2021 Document type: Article Affiliation country: India Country of publication: Italy