Drug-mediated ion suppression and mitigation of interferences using liquid chromatography-quadrupole/time of flight mass spectrometry (LC-Q/TOF-MS) and liquid chromatography tandem mass spectrometry (LC-MS/MS).

Skillman, Britni; Kerrigan, Sarah

Skillman, Britni; Kerrigan, Sarah.

Affiliation

Skillman B; Sam Houston State University, Department of Forensic Science, 1003 Bowers Blvd., Huntsville, TX 77341, USA.
Kerrigan S; Sam Houston State University, Department of Forensic Science, 1003 Bowers Blvd., Huntsville, TX 77341, USA. Electronic address: sarah.kerrigan@shsu.edu.

J Chromatogr B Analyt Technol Biomed Life Sci ; 1152: 122265, 2020 Sep 01.

Article in En | MEDLINE | ID: mdl-32721861

Subject(s)

Chromatography, Liquid/methods; Ions; Pharmaceutical Preparations; Tandem Mass Spectrometry/methods; Azepines; Forensic Toxicology/methods; Forensic Toxicology/standards; Ions/analysis; Ions/chemistry; Models, Chemical; Pharmaceutical Preparations/analysis; Pharmaceutical Preparations/chemistry; Reference Standards; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization/methods; Triazoles

Key words

Forensic toxicology; Interferences; Ion suppression; LC-MS/MS; LC-Q/TOF-MS; Suvorexant

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pharmaceutical Preparations / Chromatography, Liquid / Tandem Mass Spectrometry / Ions Type of study: Prognostic_studies Language: En Journal: J Chromatogr B Analyt Technol Biomed Life Sci Journal subject: ENGENHARIA BIOMEDICA Year: 2020 Document type: Article Affiliation country: United States Country of publication: Netherlands

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