Drug Resistance Mutations and Associated Phenotypes Detected in Clinical Trials of Maribavir for Treatment of Cytomegalovirus Infection.

Chou, Sunwen; Song, Kening; Wu, Jingyang; Bo, Tien; Crumpacker, Clyde

Chou, Sunwen; Song, Kening; Wu, Jingyang; Bo, Tien; Crumpacker, Clyde.

Affiliation

Chou S; Oregon Health and Science University and Veterans Affairs Health Care System, Portland, Oregon, USA.
Song K; Shire Human Genetic Therapies Inc., a Takeda Company, Lexington, Massachusetts, USA.
Wu J; Shire Human Genetic Therapies Inc., a Takeda Company, Lexington, Massachusetts, USA.
Bo T; Shire Human Genetic Therapies Inc., a Takeda Company, Lexington, Massachusetts, USA.
Crumpacker C; Harvard Beth Israel-Deaconess Medical Center, Boston, Massachusetts, USA.

J Infect Dis ; 226(4): 576-584, 2022 09 04.

Article in En | MEDLINE | ID: mdl-32726419

Subject(s)

Cytomegalovirus Infections; Cytomegalovirus; Humans; Cytomegalovirus/genetics; Drug Resistance, Viral/genetics; Antiviral Agents/pharmacology; Antiviral Agents/therapeutic use; Phosphotransferases (Alcohol Group Acceptor)/genetics; Phosphotransferases (Alcohol Group Acceptor)/therapeutic use; Cytomegalovirus Infections/drug therapy; Ganciclovir/pharmacology; Ganciclovir/therapeutic use; Mutation; Phenotype

Key words

antiviral drug resistance; antiviral therapy; cytomegalovirus; kinase; maribavir

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytomegalovirus Infections / Cytomegalovirus Type of study: Risk_factors_studies Limits: Humans Language: En Journal: J Infect Dis Year: 2022 Document type: Article Affiliation country: United States Country of publication: United States

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