Does the use of preoperative bisphosphonates in patients with osteopenia and osteoporosis affect lumbar fusion rates? Analysis from a national spine registry.

Guppy, Kern H; Chan, Priscilla H; Prentice, Heather A; Norheim, Elizabeth P; Harris, Jessica E; Brara, Harsimran S

Guppy, Kern H; Chan, Priscilla H; Prentice, Heather A; Norheim, Elizabeth P; Harris, Jessica E; Brara, Harsimran S.

Affiliation

Guppy KH; 1Department of Neurosurgery, The Permanente Medical Group, Sacramento.
Chan PH; 2Surgical Outcomes & Analysis, Kaiser Permanente, San Diego.
Prentice HA; 2Surgical Outcomes & Analysis, Kaiser Permanente, San Diego.
Norheim EP; 3Department of Spinal Surgery, Southern California Permanente Medical Group, Downey; and.
Harris JE; 2Surgical Outcomes & Analysis, Kaiser Permanente, San Diego.
Brara HS; 4Department of Neurosurgery, Southern California Permanente Medical Group, Los Angeles, California.

Neurosurg Focus ; 49(2): E12, 2020 08.

Article in En | MEDLINE | ID: mdl-32738794

Subject(s)

Bone Diseases, Metabolic/surgery; Diphosphonates/administration & dosage; Lumbar Vertebrae/surgery; Osteoporosis/surgery; Preoperative Care/trends; Registries; Spinal Fusion/trends; Aged; Bone Diseases, Metabolic/drug therapy; Bone Diseases, Metabolic/epidemiology; Cohort Studies; Female; Follow-Up Studies; Humans; Lumbar Vertebrae/diagnostic imaging; Male; Middle Aged; Osteoporosis/drug therapy; Osteoporosis/epidemiology; Postoperative Complications/diagnostic imaging; Postoperative Complications/epidemiology; Postoperative Complications/prevention & control; Retrospective Studies; Spinal Fusion/adverse effects; Treatment Outcome

Key words

ALIF = anterior lumbar interbody fusion with pedicle screws; BMP = bone morphogenic protein; CIF = cumulative incidence function; CPT = Current Procedural Terminology; DEXA = dual-energy x-ray absorptiometry; EHR = electronic health record; PLF = posterolateral lumbar fusion with pedicle screws; PLIF = posterior lumbar interbody fusion with pedicle screws; RCT = randomized controlled trial; TLIF = transforaminal lumbar interbody fusion with pedicle screws; ZA = zoledronic acid; bisphosphonates; lumbar fusion; nonunion; osteopenia; osteoporosis; pseudarthrosis; reoperation; retrospective; spine registry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteoporosis / Spinal Fusion / Bone Diseases, Metabolic / Preoperative Care / Registries / Diphosphonates / Lumbar Vertebrae Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: Neurosurg Focus Journal subject: NEUROCIRURGIA Year: 2020 Document type: Article

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