Opposite Roles of NT-3 and BDNF in Synaptic Remodeling of the Inner Ear Induced by Electrical Stimulation.

Li, Qiang; Chen, Min; Zhang, Chen; Lu, Tianhao; Min, Shiyao; Li, Shufeng

Li, Qiang; Chen, Min; Zhang, Chen; Lu, Tianhao; Min, Shiyao; Li, Shufeng.

Affiliation

Li Q; ENT Institute and Department of Otolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Chen M; NHC Key Laboratory of Hearing Medicine (Fudan University), Shanghai, China.
Zhang C; ENT Institute and Department of Otolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Lu T; NHC Key Laboratory of Hearing Medicine (Fudan University), Shanghai, China.
Min S; ENT Institute and Department of Otolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Li S; NHC Key Laboratory of Hearing Medicine (Fudan University), Shanghai, China.

Cell Mol Neurobiol ; 41(8): 1665-1682, 2021 Nov.

Article in En | MEDLINE | ID: mdl-32770528

Subject(s)

Brain-Derived Neurotrophic Factor/biosynthesis; Ear, Inner/metabolism; Neuronal Plasticity/drug effects; Neurotrophin 3/biosynthesis; Synapses/drug effects; Synapses/metabolism; Animals; Brain-Derived Neurotrophic Factor/administration & dosage; Ear, Inner/drug effects; Electric Stimulation/methods; Guinea Pigs; Male; Neuronal Plasticity/physiology; Neurotrophin 3/administration & dosage

Key words

Brain derived neurotrophic factor (BDNF); Cochlear implant (CI); Electrical stimulation; Neurotrophin-3 (NT-3); Synaptic remodeling

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Synapses / Brain-Derived Neurotrophic Factor / Neurotrophin 3 / Ear, Inner / Neuronal Plasticity Type of study: Prognostic_studies Limits: Animals Language: En Journal: Cell Mol Neurobiol Year: 2021 Document type: Article Affiliation country: China Country of publication: United States

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