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An Injectable Microparticle Formulation Provides Long-Term Inhibition of Hypothalamic ERK1/2 Activity and Sympathetic Excitation in Rats with Heart Failure.
Naguib, Youssef W; Yu, Yang; Wei, Shun-Guang; Morris, Angie; Givens, Brittany E; Mekkawy, Aml I; Weiss, Robert M; Felder, Robert B; Salem, Aliasger K.
Affiliation
  • Naguib YW; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa 52242, United States.
  • Yu Y; Department of Pharmaceutics, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
  • Wei SG; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, United States.
  • Morris A; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, United States.
  • Givens BE; Iowa Neuroscience Institute, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, United States.
  • Mekkawy AI; Francois M. Abboud Cardiovascular Research Center, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, United States.
  • Weiss RM; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa 52242, United States.
  • Felder RB; Department of Pharmaceutical Sciences and Experimental Therapeutics, College of Pharmacy, University of Iowa, Iowa City, Iowa 52242, United States.
  • Salem AK; Department of Chemical and Materials Engineering, University of Kentucky, Lexington, Kentucky 40506, United States.
Mol Pharm ; 17(9): 3643-3648, 2020 09 08.
Article in En | MEDLINE | ID: mdl-32786958
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Paraventricular Hypothalamic Nucleus / Pharmaceutical Preparations / MAP Kinase Signaling System / Heart Failure Limits: Animals Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Paraventricular Hypothalamic Nucleus / Pharmaceutical Preparations / MAP Kinase Signaling System / Heart Failure Limits: Animals Language: En Journal: Mol Pharm Journal subject: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States