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Dysregulation of ghrelin in diabetes impairs the vascular reparative response to hindlimb ischemia in a mouse model; clinical relevance to peripheral artery disease.
Neale, Joshua P H; Pearson, James T; Thomas, Kate N; Tsuchimochi, Hirotsugu; Hosoda, Hiroshi; Kojima, Masayasu; Sato, Takahiro; Jones, Gregory T; Denny, Adam P; Daniels, Lorna J; Chandrasekera, Dhananjie; Liu, Ping; van Rij, Andre M; Katare, Rajesh; Schwenke, Daryl O.
Affiliation
  • Neale JPH; Department of Physiology, School of Biomedical Sciences and HeartOtago, University of Otago, 270 Great King Street, Dunedin, 9018, New Zealand.
  • Pearson JT; Department of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan.
  • Thomas KN; Biomedicine Discovery Institute and Department of Physiology, Monash University, Clayton, Australia.
  • Tsuchimochi H; Department of Surgical Sciences, University of Otago, Dunedin, New Zealand.
  • Hosoda H; Department of Cardiac Physiology, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan.
  • Kojima M; Department of Regenerative Medicine, National Cerebral and Cardiovascular Center Research Institute, Suita, Osaka, Japan.
  • Sato T; Molecular Genetics, Institute of Life Science, Kurume University, Kurume, Japan.
  • Jones GT; Molecular Genetics, Institute of Life Science, Kurume University, Kurume, Japan.
  • Denny AP; Department of Surgical Sciences, University of Otago, Dunedin, New Zealand.
  • Daniels LJ; Department of Physiology, School of Biomedical Sciences and HeartOtago, University of Otago, 270 Great King Street, Dunedin, 9018, New Zealand.
  • Chandrasekera D; Department of Physiology, School of Biomedical Sciences and HeartOtago, University of Otago, 270 Great King Street, Dunedin, 9018, New Zealand.
  • Liu P; Department of Physiology, School of Biomedical Sciences and HeartOtago, University of Otago, 270 Great King Street, Dunedin, 9018, New Zealand.
  • van Rij AM; Department of Anatomy, School of Biomedical Sciences, University of Otago, Dunedin, New Zealand.
  • Katare R; Department of Surgical Sciences, University of Otago, Dunedin, New Zealand.
  • Schwenke DO; Department of Physiology, School of Biomedical Sciences and HeartOtago, University of Otago, 270 Great King Street, Dunedin, 9018, New Zealand. rajesh.katare@otago.ac.nz.
Sci Rep ; 10(1): 13651, 2020 08 12.
Article in En | MEDLINE | ID: mdl-32788622
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Disease Models, Animal / Ghrelin / Peripheral Arterial Disease / Hindlimb / Ischemia / Neovascularization, Pathologic Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: New Zealand Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 / Disease Models, Animal / Ghrelin / Peripheral Arterial Disease / Hindlimb / Ischemia / Neovascularization, Pathologic Type of study: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limits: Aged / Animals / Female / Humans / Male / Middle aged Language: En Journal: Sci Rep Year: 2020 Document type: Article Affiliation country: New Zealand Country of publication: United kingdom