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PRDM12: New Opportunity in Pain Research.
Imhof, Sophie; Kokotovic, Tomislav; Nagy, Vanja.
Affiliation
  • Imhof S; Department of Neurology, Medical University of Vienna, Vienna, Austria.
  • Kokotovic T; Department of Neurology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
  • Nagy V; Department of Neurology, Medical University of Vienna, Vienna, Austria; Ludwig Boltzmann Institute for Rare and Undiagnosed Diseases, Vienna, Austria; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. Electronic address: VNagy@cemm.oeaw.ac.at.
Trends Mol Med ; 26(10): 895-897, 2020 10.
Article in En | MEDLINE | ID: mdl-32828702
ABSTRACT
PRDM12 is a newly identified causative gene for a type of congenital insensitivity to pain disorder, which is characterized by the inability to perceive pain. Here, we discuss the (patho)physiology of PRDM12 function and the opportunities and challenges those data provide for novel therapeutic approaches in various pain disorders.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Carrier Proteins / Nerve Tissue Proteins Limits: Animals / Humans Language: En Journal: Trends Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2020 Document type: Article Affiliation country: Austria
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pain / Carrier Proteins / Nerve Tissue Proteins Limits: Animals / Humans Language: En Journal: Trends Mol Med Journal subject: BIOLOGIA MOLECULAR Year: 2020 Document type: Article Affiliation country: Austria