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Single-cell RNA sequencing reveals profibrotic roles of distinct epithelial and mesenchymal lineages in pulmonary fibrosis.
Habermann, Arun C; Gutierrez, Austin J; Bui, Linh T; Yahn, Stephanie L; Winters, Nichelle I; Calvi, Carla L; Peter, Lance; Chung, Mei-I; Taylor, Chase J; Jetter, Christopher; Raju, Latha; Roberson, Jamie; Ding, Guixiao; Wood, Lori; Sucre, Jennifer M S; Richmond, Bradley W; Serezani, Ana P; McDonnell, Wyatt J; Mallal, Simon B; Bacchetta, Matthew J; Loyd, James E; Shaver, Ciara M; Ware, Lorraine B; Bremner, Ross; Walia, Rajat; Blackwell, Timothy S; Banovich, Nicholas E; Kropski, Jonathan A.
Affiliation
  • Habermann AC; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Gutierrez AJ; Translational Genomics Research Institute, Phoenix, AZ, USA.
  • Bui LT; Translational Genomics Research Institute, Phoenix, AZ, USA.
  • Yahn SL; Translational Genomics Research Institute, Phoenix, AZ, USA.
  • Winters NI; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Calvi CL; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Peter L; Translational Genomics Research Institute, Phoenix, AZ, USA.
  • Chung MI; Translational Genomics Research Institute, Phoenix, AZ, USA.
  • Taylor CJ; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Jetter C; Division of Neonatology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Raju L; Vanderbilt Center for Advanced Genomics, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Roberson J; Vanderbilt Center for Advanced Genomics, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Ding G; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Wood L; Department of Thoracic Disease and Transplantation, Norton Thoracic Institute, Phoenix, AZ, USA.
  • Sucre JMS; Division of Neonatology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Richmond BW; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Serezani AP; Department of Veterans Affairs Medical Center, Nashville, TN, USA.
  • McDonnell WJ; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Mallal SB; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Bacchetta MJ; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Loyd JE; Division of Infectious Diseases, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Shaver CM; Institute for Immunology and Infectious Diseases, Murdoch University, Discovery Way, Murdoch, Western Australia 6150, Australia.
  • Ware LB; Department of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Bremner R; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Walia R; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Blackwell TS; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Banovich NE; Department of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA.
  • Kropski JA; Department of Thoracic Disease and Transplantation, Norton Thoracic Institute, Phoenix, AZ, USA.
Sci Adv ; 6(28): eaba1972, 2020 07.
Article in En | MEDLINE | ID: mdl-32832598
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Fibrosis Limits: Humans Language: En Journal: Sci Adv Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Fibrosis Limits: Humans Language: En Journal: Sci Adv Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States