Escin attenuates oxidative damage, apoptosis and lipid peroxidation in a model of cyclophosphamide-induced liver damage.

Cengiz, Mustafa; Kutlu, Hatice Mehtap; Peker Cengiz, Betül; Ayhanci, Adnan

Cengiz, Mustafa; Kutlu, Hatice Mehtap; Peker Cengiz, Betül; Ayhanci, Adnan.

Affiliation

Cengiz M; Department of Elementary Education, Faculty of Education, Siirt University, Siirt, Turkey.
Kutlu HM; Department of Biology, Faculty of Science, Eskisehir Technical University, Eskisehir, Turkey.
Peker Cengiz B; Department of Pathology, Eskisehir Yunus Emre State Hospital, Eskisehir, Turkey.
Ayhanci A; Department of Biology, Faculty of Arts and Science, Eskisehir Osmangazi University, Eskisehir, Turkey.

Drug Chem Toxicol ; 45(3): 1180-1187, 2022 May.

Article in En | MEDLINE | ID: mdl-32838567

Subject(s)

Chemical and Drug Induced Liver Injury; Escin; Animals; Antioxidants/metabolism; Apoptosis; Chemical and Drug Induced Liver Injury/etiology; Chemical and Drug Induced Liver Injury/metabolism; Chemical and Drug Induced Liver Injury/prevention & control; Cyclophosphamide/toxicity; Escin/metabolism; Escin/pharmacology; Glutathione/metabolism; Lipid Peroxidation; Liver; Oxidative Stress; Rats

Key words

Escin; anti-apoptotic; cell death; cyclophosphamide; liver damage

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Escin / Chemical and Drug Induced Liver Injury Type of study: Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Drug Chem Toxicol Year: 2022 Document type: Article Affiliation country: Turkey

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