Your browser doesn't support javascript.
loading
Enhancing intracellular accumulation and target engagement of PROTACs with reversible covalent chemistry.
Guo, Wen-Hao; Qi, Xiaoli; Yu, Xin; Liu, Yang; Chung, Chan-I; Bai, Fang; Lin, Xingcheng; Lu, Dong; Wang, Lingfei; Chen, Jianwei; Su, Lynn Hsiao; Nomie, Krystle J; Li, Feng; Wang, Meng C; Shu, Xiaokun; Onuchic, José N; Woyach, Jennifer A; Wang, Michael L; Wang, Jin.
Affiliation
  • Guo WH; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Qi X; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Yu X; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Liu Y; Division of Cancer Medicine, Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Chung CI; Department of Pharmaceutical Chemistry, University of California-San Francisco, San Francisco, CA, 94158, USA.
  • Bai F; Center for Theoretical Biological Physics, Rice University, Houston, TX, 77005, USA.
  • Lin X; Department of Chemistry, Massachusetts Institute of Technology, Cambridge, MA, 02139, USA.
  • Lu D; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Wang L; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Chen J; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Su LH; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Nomie KJ; Division of Cancer Medicine, Department of Lymphoma/Myeloma, The University of Texas MD Anderson Cancer Center, Houston, TX, 77030, USA.
  • Li F; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Wang MC; Center for Drug Discovery, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Shu X; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Onuchic JN; Huffington Center on Aging, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Woyach JA; Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX, 77030, USA.
  • Wang ML; Department of Pharmaceutical Chemistry, University of California-San Francisco, San Francisco, CA, 94158, USA.
  • Wang J; Center for Theoretical Biological Physics, Rice University, Houston, TX, 77005, USA.
Nat Commun ; 11(1): 4268, 2020 08 26.
Article in En | MEDLINE | ID: mdl-32848159
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / Agammaglobulinaemia Tyrosine Kinase Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Ubiquitin-Protein Ligases / Agammaglobulinaemia Tyrosine Kinase Limits: Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2020 Document type: Article Affiliation country: United States