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Covalent inhibition of NSD1 histone methyltransferase.
Huang, Huang; Howard, Christina A; Zari, Sergei; Cho, Hyo Je; Shukla, Shirish; Li, Hao; Ndoj, Juliano; González-Alonso, Paula; Nikolaidis, Caroline; Abbott, Joshua; Rogawski, David S; Potopnyk, Mykhaylo A; Kempinska, Katarzyna; Miao, Hongzhi; Purohit, Trupta; Henderson, Andrew; Mapp, Anna; Sulis, Maria Luisa; Ferrando, Adolfo; Grembecka, Jolanta; Cierpicki, Tomasz.
Affiliation
  • Huang H; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Howard CA; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Zari S; Program in Chemical Biology, University of Michigan, Ann Arbor, MI, USA.
  • Cho HJ; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Shukla S; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Li H; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Ndoj J; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • González-Alonso P; Program in Chemical Biology, University of Michigan, Ann Arbor, MI, USA.
  • Nikolaidis C; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Abbott J; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Rogawski DS; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Potopnyk MA; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Kempinska K; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Miao H; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Purohit T; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Henderson A; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Mapp A; Department of Pathology, University of Michigan, Ann Arbor, MI, USA.
  • Sulis ML; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
  • Ferrando A; Program in Chemical Biology, University of Michigan, Ann Arbor, MI, USA.
  • Grembecka J; Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
  • Cierpicki T; Department of Pediatric Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Nat Chem Biol ; 16(12): 1403-1410, 2020 12.
Article in En | MEDLINE | ID: mdl-32868895
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Leukemic / Oncogene Proteins, Fusion / Histone-Lysine N-Methyltransferase / Nuclear Pore Complex Proteins / Enzyme Inhibitors / Leukocytes / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Leukemic / Oncogene Proteins, Fusion / Histone-Lysine N-Methyltransferase / Nuclear Pore Complex Proteins / Enzyme Inhibitors / Leukocytes / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2020 Document type: Article Affiliation country: United States Country of publication: United States