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Autism-associated variants of neuroligin 4X impair synaptogenic activity by various molecular mechanisms.
Yumoto, Takafumi; Kimura, Misaki; Nagatomo, Ryota; Sato, Tsukika; Utsunomiya, Shun; Aoki, Natsue; Kitaura, Motoji; Takahashi, Koji; Takemoto, Hiroshi; Watanabe, Hirotaka; Okano, Hideyuki; Yoshida, Fumiaki; Nao, Yosuke; Tomita, Taisuke.
Affiliation
  • Yumoto T; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
  • Kimura M; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
  • Nagatomo R; Laboratory of Neuropathology and Neuroscience, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.
  • Sato T; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
  • Utsunomiya S; Neuroscience 2, Laboratory for Drug Discovery and Disease Research, Shionogi, Osaka, Japan.
  • Aoki N; Business-Academia Collaborative Laboratory (Shionogi), Graduate School of Pharmaceutical Science, The University of Tokyo, Tokyo, Japan.
  • Kitaura M; Neuroscience 2, Laboratory for Drug Discovery and Disease Research, Shionogi, Osaka, Japan.
  • Takahashi K; Business-Academia Collaborative Laboratory (Shionogi), Graduate School of Pharmaceutical Science, The University of Tokyo, Tokyo, Japan.
  • Takemoto H; Research Administration SPRC, R&D General Administration Unit, General Administration Division, Shionogi Administration Service, Osaka, Japan.
  • Watanabe H; Drug Discovery Technology 3, Laboratory for Innovative Therapy Research, Shionogi, Osaka, Japan.
  • Okano H; Neuroscience 2, Laboratory for Drug Discovery and Disease Research, Shionogi, Osaka, Japan.
  • Yoshida F; Business-Academia Collaborative Laboratory (Shionogi), Graduate School of Pharmaceutical Science, The University of Tokyo, Tokyo, Japan.
  • Nao Y; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
  • Tomita T; Department of Physiology, Keio University School of Medicine, Tokyo, Japan.
Mol Autism ; 11(1): 68, 2020 09 01.
Article in En | MEDLINE | ID: mdl-32873342
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Synapses / Cell Adhesion Molecules, Neuronal / Mutation Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Mol Autism Year: 2020 Document type: Article Affiliation country: Japan Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autistic Disorder / Synapses / Cell Adhesion Molecules, Neuronal / Mutation Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: Mol Autism Year: 2020 Document type: Article Affiliation country: Japan Country of publication: United kingdom