Functional recovery with histomorphometric analysis of nerves and muscles after combination treatment with erythropoietin and dexamethasone in acute peripheral nerve injury.

Lee, Jung Il; Hur, Jeong Min; You, Jooyoung; Lee, Duk Hee

Lee, Jung Il; Hur, Jeong Min; You, Jooyoung; Lee, Duk Hee.

Affiliation

Lee JI; Department of Orthopedic Surgery, Hanyang University Guri Hospital, Guri, South Korea.
Hur JM; College of Medicine, Hanyang University, Seoul, South Korea.
You J; Department of Orthopedic Surgery, Hanyang University Guri Hospital, Guri, South Korea.
Lee DH; Department of Orthopedic Surgery, Hanyang University Guri Hospital, Guri, South Korea.

PLoS One ; 15(9): e0238208, 2020.

Article in En | MEDLINE | ID: mdl-32881928

Subject(s)

Dexamethasone/therapeutic use; Erythropoietin/therapeutic use; Muscles/metabolism; Peripheral Nerve Injuries/drug therapy; Sciatic Nerve/metabolism; Acute Disease; Animals; Axons/metabolism; Dexamethasone/pharmacology; Disease Models, Animal; Drug Therapy, Combination; Erythropoietin/pharmacology; Male; Mice; Mice, Inbred C57BL; Microscopy, Confocal; Muscles/pathology; Muscular Atrophy/pathology; Muscular Atrophy/prevention & control; Myelin P0 Protein/metabolism; Peripheral Nerve Injuries/pathology; Recovery of Function/drug effects; Remyelination/drug effects; Schwann Cells/cytology; Schwann Cells/metabolism; Sciatic Nerve/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Sciatic Nerve / Dexamethasone / Erythropoietin / Peripheral Nerve Injuries / Muscles Type of study: Prognostic_studies Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2020 Document type: Article Affiliation country: South Korea Country of publication: United States

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